Extracellular‐Vesicle‐Based Drug Delivery Systems for Enhanced Antitumor Therapies through Modulating the Cancer‐Immunity Cycle
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DOI: 10.1002/adma.202201054
Abstract: Although immunotherapy harnessing activity of the immune system against tumors has made great progress, the treatment efficacy remains limited in most cancers. Current anticancer immunotherapy is primarily based on T‐cell‐mediated cellular immunity, which highly relies… read more here.
Keywords: cancer immunity; immunity; immunity cycle; drug delivery ... See more keywords
Melanoma Cancer Immunotherapy Using PD-L1 siRNA and Imatinib Promotes Cancer-Immunity Cycle
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DOI: 10.1007/s11095-020-02838-4
Abstract: Purpose Cancer-Immunity Cycle is a cascade of anticancer immune responses in the body that continues and fights against the cancer expansion. The Cancer-Immunity Cycle is halted by tumor cell immunosuppression of host T cell through… read more here.
Keywords: immunity; immunity cycle; cancer immunity; cancer ... See more keywords
Symphony of nanomaterials and immunotherapy based on the cancer‒immunity cycle
Sign Up to like & getrecommendations! Published in 2021 at "Acta Pharmaceutica Sinica B"
DOI: 10.1016/j.apsb.2021.05.031
Abstract: Abstract The immune system is involved in the initiation and progression of cancer. Research on cancer and immunity has contributed to the development of several clinically successful immunotherapies. These immunotherapies often act on a single… read more here.
Keywords: cancer; immunity cycle; cancer immunity; based cancer ... See more keywords
Abstract 1033: NANOG-HSP90A axis confers immunotherapeutic resistance by blocking anti-tumor immunity cycle
Sign Up to like & getrecommendations! Published in 2020 at "Immunology"
DOI: 10.1158/1538-7445.am2020-1033
Abstract: T cell-based immunotherapy has shifted the paradigm for cancer treatment. However, the majority of patients lack effective responses due to presence of immune-refractory tumor cells that limits its clinical success by blocking amplification of anti-tumor… read more here.
Keywords: hsp90a; tumor immunity; anti tumor; immunity cycle ... See more keywords
Comprehensive Analysis of a Cancer-Immunity Cycle–Based Signature for Predicting Prognosis and Immunotherapy Response in Patients With Colorectal Cancer
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DOI: 10.3389/fimmu.2022.892512
Abstract: Immune checkpoint blockade (ICB) has been recognized as a promising immunotherapy for colorectal cancer (CRC); however, most patients have little or no clinical benefit. This study aimed to develop a novel cancer-immunity cycle–based signature to… read more here.
Keywords: immunotherapy; cancer immunity; immunity cycle; cancer ... See more keywords
Circadian and Immunity Cycle Talk in Cancer Destination: From Biological Aspects to In Silico Analysis
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DOI: 10.3390/cancers14061578
Abstract: Simple Summary The circadian cycle is a natural cycle of the body repeated every 24 h, based on a day and night rhythm, and it affects many body processes. The present article reviews the importance… read more here.
Keywords: cycle; circadian cycle; circadian immunity; immunity cycle ... See more keywords
A Comprehensive View of the Cancer-Immunity Cycle (CIC) in HPV-Mediated Cervical Cancer and Prospects for Emerging Therapeutic Opportunities
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DOI: 10.3390/cancers15041333
Abstract: Simple Summary Every year, cervical cancer affects more than 500,000 women worldwide. The persistent infection caused by the human papillomavirus (HPV) is the main risk factor for the development of this type of cancer. Conventional… read more here.
Keywords: cervical cancer; cic; cancer immunity; hpv ... See more keywords