NLRC4 biology in immunity and inflammation
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.3mr0420-573r
Abstract: Inflammasomes are cytosolic multiprotein complexes that sense microbial infections or host cell damage, triggering cytokine production and a proinflammatory form of cell death, called pyroptosis. Whereas pyroptosis and cytokine production may often promote host resistance… read more here.
Keywords: activation; immunity inflammation; biology; biology immunity ... See more keywords
Key Roles of MiT Transcription Factors in Innate Immunity and Inflammation.
Sign Up to like & getrecommendations! Published in 2020 at "Trends in immunology"
DOI: 10.1016/j.it.2019.12.003
Abstract: Microphthalmia/TFE (MiT) transcription factors (TFs), such as transcription factor EB (TFEB) and transcription factor E3 (TFE3), are emerging as key regulators of innate immunity and inflammation. Rapid progress in the field requires a focused update… read more here.
Keywords: transcription; inflammation; immunity inflammation; mit transcription ... See more keywords
Wandering pathways in the regulation of innate immunity and inflammation.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of autoimmunity"
DOI: 10.1016/j.jaut.2017.10.007
Abstract: Tumor-associated macrophages (TAM) have served as a paradigm of cancer-related inflammation. Moreover, investigations on TAM have led to the dissection of macrophage plasticity and polarization and to the discovery and analysis of molecular pathways of… read more here.
Keywords: regulation innate; immunity; inflammation; immunity inflammation ... See more keywords
The role of O-GlcNAcylation in innate immunity and inflammation
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Molecular Cell Biology"
DOI: 10.1093/jmcb/mjac065
Abstract: Abstract O-linked β-N-acetylglucosaminylation (O-GlcNAcylation) is a highly dynamic and widespread post-translational modification (PTM) that regulates the activity, subcellular localization, and stability of target proteins. O-GlcNAcylation is a reversible PTM controlled by two cycling enzymes: O-linked… read more here.
Keywords: immunity inflammation; innate immunity; glcnacylation innate; glcnacylation ... See more keywords
Oxysterols in intestinal immunity and inflammation
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Internal Medicine"
DOI: 10.1111/joim.12855
Abstract: Cholesterol is an essential molecule for life. It is a component of the cell membrane, and it is a precursor molecule for bile acids, vitamin D and steroid hormones. Cholesterol is actively metabolized, but the… read more here.
Keywords: inflammation; cholesterol; immunity inflammation; oxysterols intestinal ... See more keywords
Role of Butylphthalide in Immunity and Inflammation: Butylphthalide May Be a Potential Therapy for Anti-Inflammation and Immunoregulation
Sign Up to like & getrecommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/7232457
Abstract: Inflammation and immunity play an essential role in disease pathogenesis. 3-N-Butylphthalide (NBP), a group of compounds extracted from seeds of Apium graveolens (Chinese celery), has been demonstrated as an efficient and effective therapy for ischemic… read more here.
Keywords: inflammation; immunity inflammation; immunity; therapy ... See more keywords
Circulating Platelets as Mediators of Immunity, Inflammation, and Thrombosis
Sign Up to like & getrecommendations! Published in 2018 at "Circulation Research"
DOI: 10.1161/circresaha.117.310795
Abstract: Platelets, non-nucleated blood components first described over 130 years ago, are recognized as the primary cell regulating hemostasis and thrombosis. The vascular importance of platelets has been attributed to their essential role in thrombosis, mediating… read more here.
Keywords: inflammation thrombosis; platelets mediators; circulating platelets; immunity inflammation ... See more keywords
Immunity and Inflammation in Atherosclerosis
Sign Up to like & getrecommendations! Published in 2019 at "Circulation Research"
DOI: 10.1161/circresaha.118.313591
Abstract: There is now overwhelming experimental and clinical evidence that atherosclerosis is a chronic inflammatory disease. Lessons from genome-wide association studies, advanced in vivo imaging techniques, transgenic lineage tracing mice, and clinical interventional studies have shown… read more here.
Keywords: immunity inflammation; inflammation atherosclerosis; immunity; atherosclerosis ... See more keywords
The Influence of Arginine Methylation in Immunity and Inflammation
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Inflammation Research"
DOI: 10.2147/jir.s364190
Abstract: Abstract Exploration in the field of epigenetics has revealed that protein arginine methyltransferases (PRMTs) contribute to disease, and this has given way to the development of specific small molecule compounds that inhibit arginine methylation. Protein… read more here.
Keywords: immunity inflammation; methylation; arginine methylation; influence arginine ... See more keywords
Editorial: Neutrophil Functions in Host Immunity, Inflammation and Tissue Repair
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.810346
Abstract: Neutrophils are the most abundant circulating leukocytes in humans and are amongst the first responders to be recruited to sites of injury and infection in response to inflammatory cues. These short-lived cells are formed by… read more here.
Keywords: inflammation tissue; tissue; host immunity; immunity inflammation ... See more keywords
Interleukin-18 cytokine in immunity, inflammation, and autoimmunity: Biological role in induction, regulation, and treatment
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.919973
Abstract: Interleukin-18 (IL-18) is a potent pro-inflammatory cytokine involved in host defense against infections and regulates the innate and acquired immune response. IL-18 is produced by both hematopoietic and non-hematopoietic cells, including monocytes, macrophages, keratinocytes and… read more here.
Keywords: cytokine; role; immunity inflammation; autoimmunity ... See more keywords