Casting a Wide Net around Immunity to Malaria Catches p53.
Sign Up to like & getrecommendations! Published in 2019 at "Immunity"
DOI: 10.1016/j.immuni.2019.09.011
Abstract: The mechanisms underlying acquisition of naturally acquired immunity to malaria are poorly understood. In this issue of Immunity, Tran and colleagues (2019) demonstrate that systems immunology is a powerful tool to decipher molecular and cellular… read more here.
Keywords: immunity; immunity malaria; net around; around immunity ... See more keywords
Evaluating antidisease immunity to malaria and implications for vaccine design
Sign Up to like & getrecommendations! Published in 2018 at "Immunology"
DOI: 10.1111/imm.12877
Abstract: Immunity to malaria could be categorized broadly as antiparasite or antidisease immunity. While most vaccine research efforts have focused on antiparasite immunity, the evidence from endemic populations suggest that antidisease immunity is an important component… read more here.
Keywords: evaluating antidisease; immunity malaria; immunity; antidisease immunity ... See more keywords
Innate immunity to malaria—The role of monocytes
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DOI: 10.1111/imr.12830
Abstract: Monocytes are innate immune cells essential for host protection against malaria. Upon activation, monocytes function to help reduce parasite burden through phagocytosis, cytokine production, and antigen presentation. However, monocytes have also been implicated in the… read more here.
Keywords: malaria role; monocytes innate; immunity malaria; role monocytes ... See more keywords
Enhanced acquired antibodies to a chimeric Plasmodium falciparum antigen; UB05‐09 is associated with protective immunity against malaria
Sign Up to like & getrecommendations! Published in 2017 at "Parasite Immunology"
DOI: 10.1111/pim.12445
Abstract: It has been shown that covalently linking two antigens could enhance the immunogenicity of the chimeric construct. To prioritize such a chimera for malaria vaccine development, it is necessary to demonstrate that naturally acquired antibodies… read more here.
Keywords: malaria; immunity malaria; acquired antibodies; chimera ... See more keywords
Anti-merozoite antibodies induce natural killer cell effector function and are associated with immunity against malaria
Sign Up to like & getrecommendations! Published in 2023 at "Science Translational Medicine"
DOI: 10.1126/scitranslmed.abn5993
Abstract: Natural killer (NK) cells are potent immune effectors that can be activated via antibody-mediated Fc receptor engagement. Using multiparameter flow cytometry, we found that NK cells degranulate and release IFN-γ upon stimulation with antibody-opsonized Plasmodium… read more here.
Keywords: cell; natural killer; antibody; immunity malaria ... See more keywords
Acquired Clinical Immunity to Malaria in Nonhuman Primates Coinfected with Schistosoma and Plasmodium Parasites
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DOI: 10.1128/iai.00464-21
Abstract: Naturally acquired immunity to malaria develops over several years and can be compromised by concomitant infections. This study explored the influence of chronic schistosomiasis on clinical outcome and immunity to repeated malaria infection. ABSTRACT Naturally… read more here.
Keywords: group; immunity; infection; clinical immunity ... See more keywords