The immunity-related GTPase IRGC mediates interaction between lipid droplets and mitochondria to facilitate sperm motility.
Sign Up to like & getrecommendations! Published in 2023 at "FEBS letters"
DOI: 10.1002/1873-3468.14640
Abstract: The immunity-related GTPases (IRGs) belong to the interferon-inducible GTPase protein family, which mediates cell-autonomous and innate immunity response to intracellular pathogens. Yet, the cellular and physiological function of IRGC, a member of the IRG subfamily,… read more here.
Keywords: immunity related; lipid droplets; immunity; sperm motility ... See more keywords
Differential Expression of Immunity Related Genes Can Predict Moderate-Severe Chronic GvHD Early after Myeloablative Hematopoietic Stem Cell Transplantation.
Sign Up to like & getrecommendations! Published in 2019 at "Biology of Blood and Marrow Transplantation"
DOI: 10.1016/j.bbmt.2018.12.231
Abstract: Introduction Chronic graft versus host disease is the major cause of poor outcomes after allogeneic hematopoietic cell transplantation (HCT). Clinically significant moderate-severe chronic GvHD (cGvHD) rarely shows a sustained complete response to immunosuppressive drugs and… read more here.
Keywords: moderate severe; related genes; chronic; transplantation ... See more keywords
Immunity-related GTPase induces lipophagy to prevent excess hepatic lipid accumulation
Sign Up to like & getrecommendations! Published in 2020 at "Journal of hepatology"
DOI: 10.1016/j.jhep.2020.04.031
Abstract: Background & Aims: Currently, only a few genetic variants explain the heritability of fatty liver disease. Quantitative trait loci (QTL) analysis of mouse strains has identified the susceptibility locus Ltg/NZO (liver triglycerides from New Zealand… read more here.
Keywords: hepatic lipid; fat diet; ifgga2; ltg nzo ... See more keywords
MicroRNA-214 regulates immunity-related genes in bovine mammary epithelial cells by targeting NFATc3 and TRAF3.
Sign Up to like & getrecommendations! Published in 2017 at "Molecular and cellular probes"
DOI: 10.1016/j.mcp.2017.06.002
Abstract: In human, microRNA-214 (miR-214) plays crucial roles in mechanisms of immunity. However, the potential importance of miR-214 in immune mechanisms in dairy cows has not been investigated. In this study, we assessed potential immunity-related functions… read more here.
Keywords: immunity; nfatc3 traf3; microrna 214; mir 214 ... See more keywords
Wolbachia‐induced expression of kenny gene in testes affects male fertility in Drosophila melanogaster
Sign Up to like & getrecommendations! Published in 2019 at "Insect Science"
DOI: 10.1111/1744-7917.12730
Abstract: Wolbachia are Gram‐negative endosymbionts that are known to cause embryonic lethality when infected male insects mate with uninfected females or with females carrying a different strain of Wolbachia, a situation characterized as cytoplasmic incompatibility (CI).… read more here.
Keywords: melanogaster; immunity related; drosophila melanogaster; wolbachia induced ... See more keywords
Genetic diversity and population structure of African village dogs based on microsatellite and immunity-related molecular markers
Sign Up to like & getrecommendations! Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0199506
Abstract: The village and street dogs represent a unique model of canine populations. In the absence of selective breeding and veterinary care, they are subject mostly to natural selection. Their analyses contribute to understanding general mechanisms… read more here.
Keywords: diversity; genetic diversity; village dogs; immunity related ... See more keywords
Evaluation of Th2 and Th17 Immunity-Related Factors as Indicators of Brucellosis
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2021.786994
Abstract: Objective Brucellosis is a common bacterial zoonotic infection, and greater than half a million new cases are diagnosed annually. This study investigates the expression of Th2 and Th17 immunity-related factors (Th2-LCR lncRNA, IL-25, TRAF3IP2, and… read more here.
Keywords: th2 th17; group; immunity related; related factors ... See more keywords
Construction and verification of a novel prognostic risk model for kidney renal clear cell carcinoma based on immunity-related genes
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2023.1107294
Abstract: Background: Currently, there are no useful biomarkers or prognostic risk markers for the diagnosis of kidney renal clear cell carcinoma (KIRC), although recent research has shown that both, the onset and progression of KIRC, are… read more here.
Keywords: immunity related; kidney renal; risk; prognostic risk ... See more keywords
Inborn errors of immunity and related microbiome
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.982772
Abstract: Inborn errors of immunity (IEI) are characterized by diverse clinical manifestations that are dominated by atypical, recurrent, chronic, or severe infectious or non-infectious features, including autoimmunity, lymphoproliferative disease, granulomas, and/or malignancy, which contribute substantially to… read more here.
Keywords: immunity related; microbiota; inborn errors; disease ... See more keywords