An approach to chimeric subunit immunogen provides efficient protection against toxicity, type III and type v secretion systems of Shigella.
Sign Up to like & getrecommendations! Published in 2021 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2021.108132
Abstract: OBJECTIVES Shigellosis is one of the infectious diseases causing severe intestinal illness in human beings. Development of an effective vaccine against Shigella is a key to deal with this bacterium. The present study aimed at… read more here.
Keywords: protection; chimeric protein; immunized mice; shigella ... See more keywords
Immunological characterization of chimeras of high specificity antigens from Mycobacterium tuberculosis H37Rv.
Sign Up to like & getrecommendations! Published in 2021 at "Tuberculosis"
DOI: 10.1016/j.tube.2021.102054
Abstract: Tuberculosis remains a serious global health problem. BCG is the only prophylactic TB vaccine and it shows variable protective efficacy. Chimeric protein subunit vaccines hold great potential as stand-alone vaccines or heterologous BCG prime boosters.… read more here.
Keywords: pp31; characterization chimeras; immunized mice; tuberculosis ... See more keywords
A novel approach for construction of an inactivated typhoid vaccine candidate that effectively augments both humoral and cellular immune responses.
Sign Up to like & getrecommendations! Published in 2017 at "Vaccine"
DOI: 10.1016/j.vaccine.2017.04.084
Abstract: Salmonella enterica serovar Typhi ghost was constructed as a vaccine candidate against typhoid fever. An asd+ plasmid pJHL187 harboring a ghost cassette comprised of PhiX 174 E lysis gene stringently controlled under the convergent promotor… read more here.
Keywords: candidate; vaccine candidate; immunized mice; novel approach ... See more keywords
Oral Chlamydia vaccination induces transmucosal protection in the airway.
Sign Up to like & getrecommendations! Published in 2018 at "Vaccine"
DOI: 10.1016/j.vaccine.2018.03.015
Abstract: Although Chlamydia has been frequently detected in the gastrointestinal tracts of both humans and animals, it is not associated with any gastrointestinal pathology. We have recently shown that gastrointestinal Chlamydiamuridarum is not only non-pathogenic but… read more here.
Keywords: protection; immunized mice; chlamydia vaccination; chlamydia ... See more keywords
Development and evaluation of a new recombinant protein vaccine (YidR) against Klebsiella pneumoniae infection.
Sign Up to like & getrecommendations! Published in 2020 at "Vaccine"
DOI: 10.1016/j.vaccine.2020.03.057
Abstract: Vaccination is a promising approach to prevent Klebsiella infection; however, the high heterogeneity of strains is a limiting factor. The best antigenic target for an anti-Klebsiella vaccine should be expressed by all or most of… read more here.
Keywords: protein vaccine; klebsiella; yidr; immunized mice ... See more keywords
A Chimeric protein of CFA/I, CS6 subunits and LTB/STa toxoid protects immunized mice against enterotoxigenic Escherichia coli
Sign Up to like & getrecommendations! Published in 2017 at "Microbiology and Immunology"
DOI: 10.1111/1348-0421.12491
Abstract: Enterotoxigenic Escherichia Coli (ETEC) strains are the commonest bacteria causing diarrhea in children in developing countries and travelers to these areas. Colonization factors (CFs) and enterotoxins are the main virulence determinants in ETEC pathogenesis. Heterogeneity… read more here.
Keywords: protein; subunits ltb; escherichia coli; immunized mice ... See more keywords
Naegleria fowleri immunization modifies lymphocytes and APC of nasal mucosa
Sign Up to like & getrecommendations! Published in 2018 at "Parasite Immunology"
DOI: 10.1111/pim.12508
Abstract: We investigated whether intranasal immunization with amoebic lysates plus cholera toxin modified the populations of T and B lymphocytes, macrophages and dendritic cells by flow cytometry from nose‐associated lymphoid tissue (NALT), cervical lymph nodes (CN),… read more here.
Keywords: immunization; immunized mice; naegleria fowleri; fowleri immunization ... See more keywords
Multi-Epitope Vaccine Design Using an Immunoinformatic Approach for SARS-CoV-2
Sign Up to like & getrecommendations! Published in 2021 at "Pathogens"
DOI: 10.3390/pathogens10060737
Abstract: Through 4 June 2021, COVID-19 has caused over 172.84 million cases of infection and 3.71 million deaths worldwide. Due to its rapid dissemination and high mutation rate, it is essential to develop a vaccine harboring… read more here.
Keywords: vaccine; immunized mice; approach; sars cov ... See more keywords