Metformin as an archetype immuno-metabolic adjuvant for cancer immunotherapy
Sign Up to like & getrecommendations! Published in 2019 at "Oncoimmunology"
DOI: 10.1080/2162402x.2019.1633235
Abstract: ABSTRACT The development of a single immuno-metabolic adjuvant capable of modulating, in the appropriate direction and intensity, the complex antagonistic and symbiotic interplays between tumor cells, immune cells, and the gut microbiota may appear pharmacologically… read more here.
Keywords: archetype immuno; cancer; metformin archetype; immuno metabolic ... See more keywords
Immuno-metabolic interfaces in cardiac disease and failure.
Sign Up to like & getrecommendations! Published in 2021 at "Cardiovascular research"
DOI: 10.1093/cvr/cvab036
Abstract: The interplay between the cardiovascular system, metabolism, and inflammation plays a central role in the pathophysiology of a wide spectrum of cardiovascular diseases, including heart failure. Here, we provide an overview of the fundamental aspects… read more here.
Keywords: metabolism; metabolic interfaces; disease; interfaces cardiac ... See more keywords
Systemic Immuno-metabolic alterations in chronic obstructive pulmonary disease (COPD)
Sign Up to like & getrecommendations! Published in 2019 at "Respiratory Research"
DOI: 10.1186/s12931-019-1139-2
Abstract: BackgroundMetabolic adaptation in immune cells is necessary to modulate immune cell function as it is intricately coupled with intracellular metabolism. We aimed to characterize the metabolic state of human peripheral blood mononuclear cells (PBMCs) after… read more here.
Keywords: copd subjects; metabolic alterations; disease; copd ... See more keywords