Structure-guided design and evaluation of CRM197-scaffolded vaccine targeting GnRH for animal immunocastration
Sign Up to like & getrecommendations! Published in 2024 at "Applied Microbiology and Biotechnology"
DOI: 10.1007/s00253-024-13348-3
Abstract: Immunocastration is a humane alternative to surgical castration for controlling population and estrous behaviors in animals. Gonadotropin-releasing hormone (GnRH), the pivotal initiating hormone of the hormonal cascade in mammals, is the optimal target for immunocastration… read more here.
Keywords: crm197; guided design; structure guided; immunocastration ... See more keywords
Immunocastration in adult boars as a model for late‐onset hypogonadism
Sign Up to like & getrecommendations! Published in 2022 at "Andrology"
DOI: 10.1111/andr.13219
Abstract: While immunocastration has been studied in male pre‐pubertal pigs, data on older, sexually mature animals are limited. To understand the physiological effects of androgen deprivation in the late sexual development phase, we compared mature immunocastrated… read more here.
Keywords: average age; immunocastration adult; boars model; immunocastration ... See more keywords
INSL3 Expression in Leydig Cells is a Biomarker for Immunocastration in Boars: Transcriptional Evidence.
Sign Up to like & getrecommendations! Published in 2025 at "Andrology"
DOI: 10.1111/andr.70136
Abstract: BACKGROUND Study aimed to obtain insights into physiological responses to immunocastration in pubertal boars by evaluating effects of alternative vaccination protocols and identifying a reliable immunocastration biomarker. OBJECTIVES It was hypothesized that the timing of… read more here.
Keywords: vaccination; immunocastration; expression; biomarker ... See more keywords
Assessing salivary cortisol and testosterone as non-invasive biomarkers for GnRH-immunocastration efficiency in heavy pigs
Sign Up to like & getrecommendations! Published in 2025 at "BMC Veterinary Research"
DOI: 10.1186/s12917-025-04708-w
Abstract: Efforts to enhance animal welfare have led to the investigation of alternative methods of performing surgical castration on young pigs that induce stress and anxiety. This study was conducted to establish the efficacy of immunocastration… read more here.
Keywords: heavy pigs; salivary cortisol; cortisol testosterone; testosterone ... See more keywords
Testicular morphometry as a tool to evaluate the efficiency of immunocastration in lambs
Sign Up to like & getrecommendations! Published in 2022 at "Animal Reproduction"
DOI: 10.1590/1984-3143-ar2021-0041
Abstract: Abstract This study aimed to evaluate the efficiency of immunocastration in lambs using testicular morphometry. Thirty lambs were randomly divided into two treatments (subcutaneous administration of 1.0 mL and 0.5 mL of an anti-GnRH vaccine)… read more here.
Keywords: immunocastration; efficiency immunocastration; evaluate efficiency; testicular morphometry ... See more keywords
Effect of immunocastration on sex glands of male Mangulica (Swallow-bellied Mangalitsa) pigs
Sign Up to like & getrecommendations! Published in 2019 at "Revista Brasileira de Zootecnia"
DOI: 10.1590/rbz4820180286
Abstract: ABSTRACT The objective of this research was to study the effect of immunocastration on the morphometric characteristics of sex glands in male Swallow-bellied Mangalitsa pigs. The study included 24 animals (13 entire and 11 immunocastrated… read more here.
Keywords: glands male; bellied mangalitsa; sex glands; effect immunocastration ... See more keywords
Immunocastration as an alternative to caponization: evaluation of its effect on body and bone development and on meat color and composition
Sign Up to like & getrecommendations! Published in 2017 at "Poultry Science"
DOI: 10.3382/ps/pex191
Abstract: &NA; Caponization is associated with some morbidity and mortality, which contributes to important economic losses. This practice is executed without any pain relief (neither anesthesia nor analgesia) and can be painful and without consideration of… read more here.
Keywords: color; animal welfare; immunocastration alternative; immunocastration ... See more keywords
Effect of GnRH immunocastration on immune function in male rats
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1023104
Abstract: The present study aimed to reveal the effects of immunocastration on the development of the immune system in rats. Seventy rats were randomly assigned into two groups: Control (n = 35) and immunized (n =… read more here.
Keywords: cd4 cd8; gnrh immunization; immunocastration; cd8 cells ... See more keywords
Does Immunocastration Affect Behaviour and Body Lesions in Heavy Pigs?
Sign Up to like & getrecommendations! Published in 2022 at "Veterinary Sciences"
DOI: 10.3390/vetsci9080410
Abstract: Simple Summary Castration of piglets is routinely practiced to prevent the presence of boar taint. In Europe, around 61% of pigs are surgically castrated, 54% of which do not receive any pain-relief therapy. The increasing… read more here.
Keywords: pig production; behaviour body; body lesions; welfare ... See more keywords