Evolution of antifungals for invasive mold infections in immunocompromised hosts, then and now
Sign Up to like & getrecommendations! Published in 2023 at "Expert Review of Anti-infective Therapy"
DOI: 10.1080/14787210.2023.2207821
Abstract: ABSTRACT Introduction The current armamentarium of antifungal agents for invasive mold infections (IMI) has dramatically improved over the last 50 years. Existing therapies are, however, associated with toxicities, drug interactions, and, in some cases, therapeutic failures.… read more here.
Keywords: invasive mold; mold infections; infections immunocompromised; antifungals invasive ... See more keywords
1578. Back to Bactrim–Utilizing Preferred Prophylaxis Strategies in Immunocompromised Hosts Via a Trimethoprim-Sulfamethoxazole Rechallenge Program
Sign Up to like & getrecommendations! Published in 2018 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofy210.1406
Abstract: Abstract Background Trimethoprim sulfamethoxazole (TMP-SMX) is the preferred agent for Pneumocystis jirovecii pneumonia prophylaxis in immunocompromised hosts (ICH). However, TMP-SMX is frequently avoided due to an adverse drug reaction (ADR) history. We report on a… read more here.
Keywords: smx adr; immunocompromised hosts; smx; trimethoprim sulfamethoxazole ... See more keywords
Antigenic escape is accelerated by the presence of immunocompromised hosts
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the Royal Society B: Biological Sciences"
DOI: 10.1098/rspb.2022.1437
Abstract: The repeated emergence of SARS-CoV-2 escape mutants from host immunity has obstructed the containment of the current pandemic and poses a serious threat to humanity. Prolonged infection in immunocompromised patients has received increasing attention as… read more here.
Keywords: antigenic escape; immunocompromised patients; immunocompromised hosts; host ... See more keywords
Cell‐free next‐generation sequencing impacts diagnosis and antimicrobial therapy in immunocompromised hosts: A retrospective study
Sign Up to like & getrecommendations! Published in 2023 at "Transplant Infectious Disease"
DOI: 10.1111/tid.13954
Abstract: Cell‐free next‐generation sequencing (cfNGS) may have a unique role in the diagnosis of infectious complications in immunocompromised hosts. The rapid turnaround time and non‐invasive nature make it a promising supplement to standard of care. read more here.
Keywords: cell free; free next; next generation; immunocompromised hosts ... See more keywords
Microneedle patch for immunization of immunocompromised hosts
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.22072
Abstract: Influenza virus is a major cause of morbidity and mortality particularly in the immunocompromised host. When compared to the general population, influenzarelated hospitalization rates are four times higher and mortality ten times higher in patients… read more here.
Keywords: immunization; influenza vaccine; immunocompromised hosts; vaccine delivery ... See more keywords
The Utility of (1→3)-β-D-Glucan Testing in the Diagnosis of Coccidioidomycosis in Hospitalized Immunocompromised Patients
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Fungi"
DOI: 10.3390/jof8080768
Abstract: Coccidioidomycosis is a fungal infection endemic to the Southwestern United States which is associated with high morbidity and mortality in immunocompromised hosts. Serology is the main diagnostic tool, although less sensitive among immunocompromised hosts. (1→3)-β-D-glucan… read more here.
Keywords: coccidioides serology; serology; coccidioidomycosis; utility glucan ... See more keywords
Efficacy of Remdesivir and Neutralizing Monoclonal Antibodies in Monotherapy or Combination Therapy in Reducing the Risk of Disease Progression in Elderly or Immunocompromised Hosts Hospitalized for COVID-19: A Single Center Retrospective Study
Sign Up to like & getrecommendations! Published in 2023 at "Viruses"
DOI: 10.3390/v15051199
Abstract: Introduction: Remdesivir (REM) and monoclonal antibodies (mAbs) could alleviate severe COVID-19 in at-risk outpatients. However, data on their use in hospitalized patients, particularly in elderly or immunocompromised hosts, are lacking. Methods: All consecutive patients hospitalized… read more here.
Keywords: severe covid; progression; combination; covid ... See more keywords