Contribution of the gp120 V3 loop to envelope glycoprotein trimer stability in primate immunodeficiency viruses
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DOI: 10.1016/j.virol.2018.06.005
Abstract: The V3 loop of the human immunodeficiency virus type 1 (HIV-1) gp120 exterior envelope glycoprotein (Env) becomes exposed after CD4 binding and contacts the coreceptor to mediate viral entry. Prior to CD4 engagement, a hydrophobic… read more here.
Keywords: immunodeficiency viruses; primate immunodeficiency; gp120; loop ... See more keywords
Immunogenicity and Efficacy of a Novel Multi-Antigenic Peptide Vaccine Based on Cross-Reactivity between Feline and Human Immunodeficiency Viruses
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DOI: 10.3390/v11020136
Abstract: For the development of an effective HIV-1 vaccine, evolutionarily conserved epitopes between feline and human immunodeficiency viruses (FIV and HIV-1) were determined by analyzing overlapping peptides from retroviral genomes that induced both anti-FIV/HIV T cell-immunity… read more here.
Keywords: human immunodeficiency; hiv; vaccine; cell ... See more keywords