Role of glycosylation on the ensemble of conformations in the MUC1 immunodominant epitope
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DOI: 10.1002/psc.3229
Abstract: MUC1 is a membrane glycoprotein, which in adenocarninomas is overexpressed and exhibits truncated O‐glycosylation. Overexpression and altered glycosylation make MUC1 into a candidate for immunotherapy. Monoclonal antibodies directed against MUC1 frequently bind an immunodominant epitope… read more here.
Keywords: immunodominant epitope; role glycosylation; muc1; glycosylation ... See more keywords