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   Articles with "immunogen" as a keyword



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An approach to chimeric subunit immunogen provides efficient protection against toxicity, type III and type v secretion systems of Shigella.

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recommendations! Published in 2021 at "International immunopharmacology"

DOI: 10.1016/j.intimp.2021.108132

Abstract: OBJECTIVES Shigellosis is one of the infectious diseases causing severe intestinal illness in human beings. Development of an effective vaccine against Shigella is a key to deal with this bacterium. The present study aimed at… read more here.

Keywords: protection; chimeric protein; immunized mice; shigella ... See more keywords

Identification of a large repetitive RTX immunogen in a highly virulent Rodentibacter heylii strain.

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recommendations! Published in 2020 at "Microbes and infection"

DOI: 10.1016/j.micinf.2020.10.007

Abstract: Rodentibacter (R.) heylii is frequently detected in laboratory rodents. Repeats in toxin (RTX) toxins are considered important virulence factors of this major murine pathogen. We evaluated the virulence of a R.heylii strain negative for all… read more here.

Keywords: rodentibacter heylii; heylii strain; rtx; immunogen ... See more keywords

Protection of Litopenaeus vannamei against white spot syndrome virus by electron-irradiated inactivated vaccine and prebiotic immunogen

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recommendations! Published in 2017 at "Radiation Physics and Chemistry"

DOI: 10.1016/j.radphyschem.2016.09.020

Abstract: Abstract WSSV 1 is an infectious agent of shrimp and other crustaceans. Neither effective vaccines nor treatments are currently available for this disease. Although the immune system of shrimps is not comparable to that of… read more here.

Keywords: prebiotic immunogen; ebi wssv; immunogen; wssv vaccine ... See more keywords

Synthesis and Structure Optimization of Star Copolymers as Tunable Macromolecular Carriers for Minimal Immunogen Vaccine Delivery

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recommendations! Published in 2024 at "Bioconjugate Chemistry"

DOI: 10.1021/acs.bioconjchem.4c00273

Abstract: Minimal immunogen vaccines are being developed to focus antibody responses against otherwise challenging targets, including human immunodeficiency virus (HIV), but multimerization of the minimal peptide immunogen on a carrier platform is required for activity. Star… read more here.

Keywords: star; immunogen; star copolymer; star copolymers ... See more keywords

Cyclization Scaffolding for Improved Vaccine Immunogen Stability: Application to Tau Protein in Alzheimer's Disease

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recommendations! Published in 2024 at "Journal of chemical information and modeling"

DOI: 10.1021/acs.jcim.3c01556

Abstract: Effective scaffolding of immunogens is crucial for generating conformationally selective antibodies through active immunization, particularly in the treatment of protein misfolding diseases such as Alzheimer's and Parkinson's disease. Previous computational work has revealed that a… read more here.

Keywords: disease; immunogen; tau; protein ... See more keywords