Oncolytic vaccines increase the response to PD-L1 blockade in immunogenic and poorly immunogenic tumors
Sign Up to like & getrecommendations! Published in 2018 at "OncoImmunology"
DOI: 10.1080/2162402x.2018.1457596
Abstract: ABSTRACT Activation of immune checkpoint pathways and limited T- cell infiltration result in immunological escape of tumors. Although immune checkpoint inhibitors are currently approved for several types of cancers, the response rate is often limited… read more here.
Keywords: response; immunogenic tumors; rate; poorly immunogenic ... See more keywords
Tripartite antigen-agnostic combination immunotherapy cures established poorly immunogenic tumors
Sign Up to like & getrecommendations! Published in 2022 at "Journal for Immunotherapy of Cancer"
DOI: 10.1136/jitc-2022-004781
Abstract: Background Single-agent immunotherapy has shown remarkable efficacy in selected cancer entities and individual patients. However, most patients fail to respond. This is likely due to diverse immunosuppressive mechanisms acting in a concerted way to suppress… read more here.
Keywords: immunogenic tumors; combination immunotherapy; immunotherapy; antigen agnostic ... See more keywords
Spatiotemporal dynamics of immunogenic tumors
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DOI: 10.1142/s1793524520500448
Abstract: A mathematical model, consisting of a system of two coupled reaction-diffusion partial differential equations describing the interaction between solid tumor and immune system (termed as effector ce... read more here.
Keywords: immunogenic tumors; spatiotemporal dynamics; dynamics immunogenic;
A Dynamically Consistent Nonstandard Difference Scheme for a Discrete-Time Immunogenic Tumors Model
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DOI: 10.3390/e24070949
Abstract: This manuscript deals with the qualitative study of certain properties of an immunogenic tumors model. Mainly, we obtain a dynamically consistent discrete-time immunogenic tumors model using a nonstandard difference scheme. The existence of fixed points… read more here.
Keywords: immunogenic tumors; time; time immunogenic; discrete time ... See more keywords