Immunogenicity of Isogenic IgG in Aggregates and Immune Complexes
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DOI: 10.1371/journal.pone.0170556
Abstract: A paradox in monoclonal antibody (mAb) therapy is that despite the well-documented tolerogenic properties of deaggregated IgG, most therapeutic IgG mAb induce anti-mAb responses. To analyze CD4 T cell reactions against IgG in various physical… read more here.
Keywords: immune complexes; mab; isogenic igg; immunogenicity isogenic ... See more keywords