The Immunogenomic Landscape of Resected Intrahepatic Cholangiocarcinoma.
Sign Up to like & getrecommendations! Published in 2021 at "Hepatology"
DOI: 10.1002/hep.32150
Abstract: Cholangiocarcinoma is a deadly and highly therapy-refractory cancer of the bile ducts, with early results from immune checkpoint blockade trials showing limited responses. While recent molecular assessments have made bulk characterizations of immune profiles and… read more here.
Keywords: immune checkpoint; immunogenomic landscape; intrahepatic cholangiocarcinoma; resected intrahepatic ... See more keywords
Immunogenomic landscape of gynecologic carcinosarcoma.
Sign Up to like & getrecommendations! Published in 2020 at "Gynecologic oncology"
DOI: 10.1016/j.ygyno.2020.11.030
Abstract: OBJECTIVE Carcinosarcoma (CS) of the uterus or ovary is a rare, biphasic tumor comprising epithelial and mesenchymal elements, and exhibits more aggressive clinical features than its carcinoma counterpart. Four molecular subtypes of CS were recently… read more here.
Keywords: gynecologic carcinosarcoma; genomic aberration; landscape gynecologic; carcinosarcoma ... See more keywords
Immunogenomic landscape of dMMR tumours
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DOI: 10.1038/s41585-018-0095-9
Abstract: Immunogenomic analysis of advanced prostate cancer has identified immunological alterations associated with defective mismatch repair (dMMR) that could inform immunotherapy strategies. Overall, dMMR status was confirmed in 8.1% of patients and was associated with poor… read more here.
Keywords: dmmr; landscape dmmr; immunogenomic landscape; dmmr tumours ... See more keywords