Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer
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DOI: 10.1038/s41467-020-15315-8
Abstract: Combined PARP and immune checkpoint inhibition has yielded encouraging results in ovarian cancer, but predictive biomarkers are lacking. We performed immunogenomic profiling and highly multiplexed single-cell imaging on tumor samples from patients enrolled in a… read more here.
Keywords: cd8 cells; immunogenomic profiling; combined parp; exhausted cd8 ... See more keywords