Development and validation of a leukocyte‐associated immunoglobulin‐like receptor‐1 prognostic signature for lower‐grade gliomas
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.4945
Abstract: Leukocyte‐associated immunoglobulin‐like receptor‐1 (LAIR‐1), is an immunosuppressive receptor, widely expressed by immune cells, but the part of LAIR‐1 in glioma progression remains unclear. The purpose of this study was to explore the relationship between LAIR‐1… read more here.
Keywords: like receptor; associated immunoglobulin; leukocyte associated; receptor ... See more keywords
Engineering of Group A Streptococcus Isopeptide Bonds into Immunoglobulin-Like Protein Domains.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0467-0_30
Abstract: Intramolecular isopeptide bonds, formed autocatalytically between Lys and Asn/Asp side chains, are widely present in the immunoglobulin-like domains of Gram-positive bacterial adhesins, including Group A Streptococcus, and confer considerable mechanical and chemical stability. These properties… read more here.
Keywords: isopeptide bonds; group streptococcus; engineering group; immunoglobulin like ... See more keywords
Hemolin, an immunoglobulin-like peptide, opsonizes nonself targets for phagocytosis and encapsulation in Spodoptera exigua, a lepidopteran insect
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Asia-Pacific Entomology"
DOI: 10.1016/j.aspen.2019.08.002
Abstract: Abstract Hemolin is an immunoglobulin-like peptide that plays crucial role in microbial pathogen surveillance. However, its specific molecular actions in immune responses remain largely unclear. This study focused on the modulation of hemocyte phagocytosis of… read more here.
Keywords: immunoglobulin like; like peptide; hemolin immunoglobulin; spodoptera exigua ... See more keywords
Killer cell immunoglobulin-like receptor genotypes in a Chilean population from Talca.
Sign Up to like & getrecommendations! Published in 2018 at "Human immunology"
DOI: 10.1016/j.humimm.2018.06.007
Abstract: Ninety healthy and unrelated volunteers were randomly selected to study the gene frequencies of Killer-cell immunoglobulin-like receptors (KIRs) in a Chilean (Talca) population. KIR typing was resolved by PCR-single specific primer (SSP), and their gene… read more here.
Keywords: population; cell immunoglobulin; killer cell; immunoglobulin like ... See more keywords
Killer immunoglobulin like receptor gene profiling in Western Indian population.
Sign Up to like & getrecommendations! Published in 2019 at "Human immunology"
DOI: 10.1016/j.humimm.2019.03.010
Abstract: One hundred and sixty one healthy unrelated hematopoietic stem cell transplant donors from Western Indian were enrolled in this study. The study was initiated to observe the genotypic diversity of 16 killer immunoglobulin like receptor… read more here.
Keywords: immunoglobulin like; like receptor; western indian; population ... See more keywords
Genotype B of Killer Cell Immunoglobulin-Like Receptor is Related with Gastric Cancer Lesions
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-24464-2
Abstract: NK cells are important in innate immunity for their capacity to kill infected or cancer cells. The killer cell immunoglobulin-like receptors (KIR) are a family of polymorphic genes with inhibitory and activating functions. The main… read more here.
Keywords: killer cell; gastric cancer; cancer; cell immunoglobulin ... See more keywords
Distribution of killer cell immunoglobulin-like receptor (KIR) genes in a large, multi-centre cohort of Chinese donors
Sign Up to like & getrecommendations! Published in 2021 at "Annals of Human Biology"
DOI: 10.1080/03014460.2021.1913223
Abstract: Abstract Background The killer cell immunoglobulin-like receptor (KIR), which mediates the killing function of NK cells, is an attractive candidate for adoptive cellular therapy. The ethnic distribution for China provides a unique opportunity to investigate… read more here.
Keywords: kir; kir genes; killer cell; cell immunoglobulin ... See more keywords
Successful Retransplantation With Killer Cell Immunoglobulin-like Receptor Ligand-mismatched Cord Blood in Infant Acute Lymphoblastic Leukemia That Relapsed After Transplantation.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of pediatric hematology/oncology"
DOI: 10.1097/mph.0000000000002614
Abstract: The prognosis of children with KMT2A-rearranged (KMT2A-r) acute lymphoblastic leukemia (ALL) remains dismal. This report describes the successful retransplantation of a patient with infant ALL who relapsed both bone marrow and central nervous system. The… read more here.
Keywords: receptor ligand; like receptor; ligand mismatched; killer cell ... See more keywords
Sialic acid‐binding immunoglobulin‐like lectin (Sigelac)‐15 is a rapidly internalised cell‐surface antigen expressed by acute myeloid leukaemia cells
Sign Up to like & getrecommendations! Published in 2021 at "British Journal of Haematology"
DOI: 10.1111/bjh.17496
Abstract: Sialic acid‐binding immunoglobulin‐like lectin (Siglec)‐15 has recently been identified as a critical tumour checkpoint, augmenting the expression and function of programmed death‐ligand 1. We raised a monoclonal antibody, A9E8, specific for Siglec‐15 using phage display.… read more here.
Keywords: immunoglobulin like; myeloid leukaemia; binding immunoglobulin; acid binding ... See more keywords
Immunoglobulin‐like transcript 2 blockade restores antitumor immune responses in glioblastoma
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Science"
DOI: 10.1111/cas.15575
Abstract: Glioblastoma stands as the most frequent primary brain tumor. Despite the multimodal therapy for glioblastoma patients, the survival rate is very low, highlighting the need for novel therapies that improve patient outcomes. Immune checkpoint blockade… read more here.
Keywords: responses glioblastoma; transcript blockade; blockade; like transcript ... See more keywords
Association between killer cell immunoglobulin‐like receptor 2DS5 gene with essential hypertension in the Chinese Han patients
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Immunogenetics"
DOI: 10.1111/iji.12342
Abstract: Hypertension has been suggested to be mediated by immunity and inflammation. As immune system genes, killer cell immunoglobulin‐like receptors (KIRs) genes play an important role in the pathogenesis of autoimmune diseases. We conducted a community… read more here.
Keywords: killer cell; immunoglobulin like; hypertension; gene ... See more keywords