What Targets Somatic Hypermutation to the Immunoglobulin Loci?
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DOI: 10.1089/vim.2019.0149
Abstract: One of the most profound enigmas in B cell biology is how activation-induced deaminase (AID) is targeted to a very small region of DNA in the immunoglobulin loci. Two specific regions are singled out: the… read more here.
Keywords: immunoglobulin loci; transcription; aid; somatic hypermutation ... See more keywords