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Published in 2018 at "Journal of Clinical Immunology"
DOI: 10.1007/s10875-018-0562-3
Abstract: PurposePrimary immunodeficiency diseases (PIDDs) are a heterogenous group of disorders characterized by intrinsic impairment in the immune system. Most patients with PIDD require life-long immunoglobulin G replacement therapy, which has been shown to reduce the…
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Keywords:
replacement therapy;
immunodeficiency;
immunoglobulin replacement;
treatment ... See more keywords
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Published in 2022 at "Bone Marrow Transplantation"
DOI: 10.1038/s41409-022-01680-z
Abstract: The efficacy of immunoglobulin replacement therapy (IgRT) has been demonstrated for primary immune deficiency diseases and hematological malignancies such as chronic lymphocytic leukemia (CLL) or multiple myeloma with hypogammaglobulinemia. Clinical development of anti-B cell therapies…
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Keywords:
therapy;
controversies immunoglobulin;
immunoglobulin replacement;
hsct ... See more keywords
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Published in 2023 at "Expert Review of Hematology"
DOI: 10.1080/17474086.2023.2176843
Abstract: ABSTRACT Introduction Secondary antibody deficiencies (SAD) are often a side effect of specific therapies that target B cells directly or affect the antibody response indirectly. Treatment of immunodeficiency by immunoglobulin replacement therapy (IgRT) is well…
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Keywords:
replacement;
replacement therapy;
immunoglobulin replacement;
deficiency ... See more keywords
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Published in 2018 at "Medicine"
DOI: 10.1097/md.0000000000012804
Abstract: Rationale: Subcutaneous immunoglobulin administration facilitated by recombinant human hyaluronidase is a new mode of immunoglobulin replacement. It has been approved for treatment in primary and secondary antibody immunodeficiency. To date, it has not been reported…
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Keywords:
immunodeficiency;
pregnancy;
immunoglobulin replacement;
case ... See more keywords
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Published in 2017 at "Internal Medicine Journal"
DOI: 10.1111/imj.81_13578
Abstract: ple well defined hypo-echoic lesions were demonstrated within the bowel wall suggesting a lymphoma. A laparotomy was performed and a very thickened distal terminal ileum and caecum was noted. No bowel biopsies were obtained because…
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Keywords:
replacement;
replacement therapy;
subcutaneous immunoglobulin;
immunoglobulin replacement ... See more keywords
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Published in 2019 at "Pediatric Transplantation"
DOI: 10.1111/petr.13625
Abstract: X‐linked agammaglobulinemia (XLA) is a primary antibody disorder due to a mutation in the Bruton tyrosine kinase gene that requires lifelong immunoglobulin replacement resulting in a significant economic burden and treatment abandonment. Hematopoietic stem cell…
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Keywords:
immunoglobulin replacement;
treosulfan;
stem cell;
transplantation ... See more keywords
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Published in 2023 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2023.1135812
Abstract: Chronic lymphocytic leukaemia (CLL) is a malignancy of clonally expanded antigen-switched, neoplastic, mature B cells. CLL is characterised by a variable degree of immunosuppression and secondary hypogammaglobulinemia. B-cell depleting therapies have historically been deployed with…
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Keywords:
cell;
immunoglobulin replacement;
therapy;
immunoglobulin ... See more keywords