An immunoinformatic approach to universal therapeutic vaccine design against BK virus.
Sign Up to like & getrecommendations! Published in 2019 at "Vaccine"
DOI: 10.1016/j.vaccine.2019.04.096
Abstract: In kidney transplant recipients (KTRs) long-term immunosuppression leads to BK virus (BKV) reactivation, with an increased incidence of BKV-associated pathologies and allograft rejection. The current approaches to limit BKV infection include a reduction in immunosuppression… read more here.
Keywords: approach universal; immunoinformatic approach; universal therapeutic; bkv ... See more keywords
Development of Multi-Epitope Vaccine constructs for Non-Small Cell Lung Cancer (NSCLC) Against USA Human Leukocyte Antigen Background: an Immunoinformatic approach toward future vaccine designing.
Sign Up to like & getrecommendations! Published in 2021 at "Expert opinion on biological therapy"
DOI: 10.1080/14712598.2021.1981285
Abstract: OBJECTIVES The design of peptide-based vaccines for cancer is a promising immunotherapy that can induce a cancer-specific cytotoxic response in tumor cells. METHODS Herein, we used the immunoinformatic approach in designing a multi-epitope vaccine targeting… read more here.
Keywords: immunoinformatic approach; vaccine constructs; cancer; epitope vaccine ... See more keywords
An immunoinformatic approach to assessing the immunogenic capacity of alpha-neurotoxins in elapid snake venoms
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2023.1143437
Abstract: Introduction: Most elapid snakes produce venoms that contain alpha-neurotoxins (α-NTXs), which are proteins that cause post-synaptic blockade and paralysis in snakebite envenoming. However, existing elapid antivenoms are known for their low potency in neutralizing the… read more here.
Keywords: immunogenic capacity; approach assessing; assessing immunogenic; alpha neurotoxins ... See more keywords