Immunological evaluation in vitro of nanoparticulate impurities isolated from pharmaceutical-grade sucrose.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of pharmaceutical sciences"
DOI: 10.1016/j.xphs.2020.11.011
Abstract: Sucrose is a commonly used stabilizing excipient in protein formulations. However, recent studies have indicated the presence of nanoparticulate impurities (NPIs) in the size range of 100 - 200 nm in pharmaceutical-grade sucrose. Furthermore, isolated… read more here.
Keywords: nanoparticulate impurities; grade sucrose; vitro; pharmaceutical grade ... See more keywords
Immunological Evaluation for Personalized Interventions in Children with Tuberculosis: Should It Be Routinely Performed?
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DOI: 10.1155/2020/8235149
Abstract: Childhood tuberculosis (TB) is a significant public health problem and the ninth leading cause of death worldwide. Progression of Mycobacterium tuberculosis infection to active disease depends on mycobacterial virulence, environmental diversity, and host susceptibility and… read more here.
Keywords: evaluation personalized; personalized interventions; interventions children; tuberculosis ... See more keywords
Synthesis and Immunological Evaluation of Mannosylated Desmuramyl Dipeptides Modified by Lipophilic Triazole Substituents
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DOI: 10.3390/ijms23158628
Abstract: Muramyl dipeptide (N-acetylmuramyl-L-alanyl-D-isoglutamine, MDP) is the smallest peptidoglycan fragment able to trigger an immune response by activating the NOD2 receptor. Structural modification of MDP can lead to analogues with improved immunostimulating properties. The aim of… read more here.
Keywords: lipophilic triazole; evaluation mannosylated; immunological evaluation; synthesis immunological ... See more keywords
Immunological Evaluation in Patients with Familial Mediterranean fever
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DOI: 10.3889/oamjms.2018.079
Abstract: OBJECTIVE: This study aimed to investigate T & B lymphocyte subsets and Natural Killer (NK) cells patterns in children with FMF versus normal control subjects, to estimate the immunoglobulins IgG, IgM, and IgA levels, and… read more here.
Keywords: cd4 cd8; cd3 cd4; evaluation patients; patients familial ... See more keywords