Immunometabolism: Another Road to Sepsis and Its Therapeutic Targeting
Sign Up to like & getrecommendations! Published in 2018 at "Inflammation"
DOI: 10.1007/s10753-018-0939-8
Abstract: Sepsis is a major health problem all over the world. Despite its existence since the time of Hippocrates (470 BC), sepsis is still a serious medical problem for physicians working in both pediatric and adult intensive… read more here.
Keywords: sepsis; immunometabolism; road sepsis; another road ... See more keywords
An Integrated View of Immunometabolism
Sign Up to like & getrecommendations! Published in 2018 at "Cell"
DOI: 10.1016/j.cell.2017.12.025
Abstract: The worldwide obesity epidemic has emerged as a major cause of insulin resistance and Type 2 diabetes. Chronic tissue inflammation is a well-recognized feature of obesity, and the field of immunometabolism has witnessed many advances… read more here.
Keywords: view immunometabolism; immunometabolism; insulin; inflammation ... See more keywords
Triclosan Reprograms Immunometabolism and Activates the Inflammasome in Human Macrophages.
Sign Up to like & getrecommendations! Published in 2022 at "Environmental science & technology"
DOI: 10.1021/acs.est.2c05254
Abstract: To gather enough energy to respond to harmful stimuli, most immune cells quickly shift their metabolic profile. This process of immunometabolism plays a critical role in the regulation of immune cell function. Triclosan, a synthetic… read more here.
Keywords: immunometabolism; triclosan reprograms; immunometabolism activates; reprograms immunometabolism ... See more keywords
Pathogenesis of ANCA-associated vasculitis: an emerging role for immunometabolism.
Sign Up to like & getrecommendations! Published in 2020 at "Rheumatology"
DOI: 10.1093/rheumatology/keaa023
Abstract: ANCA-associated vasculitis (AAV) is a severe systemic autoimmune disease. A key feature of AAV is the presence of Anti-Neutrophil Cytoplasmic Antibodies (ANCA) directed against myeloperoxidase (MPO) or proteinase-3 (PR3). ANCA are key to the pathogenesis… read more here.
Keywords: immunometabolism; immune cell; pathogenesis; associated vasculitis ... See more keywords
Immunometabolism shapes B cell fate and functions
Sign Up to like & getrecommendations! Published in 2022 at "Immunology"
DOI: 10.1111/imm.13499
Abstract: B lymphocyte‐mediated humoral immune response is essential for protection against infectious diseases. Deeper research in B cell biology, particularly metabolism is required for the better understanding of its properties in homeostasis and in diseases. Emerging… read more here.
Keywords: cell fate; cell; metabolism; development ... See more keywords
Immunometabolism: From basic mechanisms to translation
Sign Up to like & getrecommendations! Published in 2020 at "Immunological Reviews"
DOI: 10.1111/imr.12858
Abstract: Immunometabolism has emerged as a major mechanism central to adaptive and innate immune regulation. From early observations that inflammatory cytokines were induced in obese adipose tissue and that these cytokines contributed to metabolic disease, it… read more here.
Keywords: basic mechanisms; immunometabolism; mechanisms translation; translation ... See more keywords
Intracellular and Intercellular Aspects of Macrophage Immunometabolism in Atherosclerosis.
Sign Up to like & getrecommendations! Published in 2020 at "Circulation research"
DOI: 10.1161/circresaha.119.315939
Abstract: Macrophage immunometabolism, the changes in intracellular metabolic pathways that alter the function of these highly plastic cells, has been the subject of intense interest in the past few years, in part because macrophage immunometabolism plays… read more here.
Keywords: immunometabolism atherosclerosis; aspects macrophage; macrophage immunometabolism; immunometabolism ... See more keywords
Similarities and Distinctions in the Effects of Metformin and Carbon Monoxide in Immunometabolism
Sign Up to like & getrecommendations! Published in 2019 at "Molecules and Cells"
DOI: 10.14348/molcells.2019.0016
Abstract: Immunometabolism, defined as the interaction of metabolic pathways with the immune system, influences the pathogenesis of metabolic diseases. Metformin and carbon monoxide (CO) are two pharmacological agents known to ameliorate metabolic disorders. There are notable… read more here.
Keywords: immunometabolism; metformin carbon; carbon monoxide; effects metformin ... See more keywords
Immunometabolism in the pathogenesis of vitiligo
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1055958
Abstract: Vitiligo is a common depigmenting skin disorder characterized by the selective loss of melanocytes. Autoimmunity, genetic, environmental, and biochemical etiology have been proposed in vitiligo pathogenesis. However, the exact molecular mechanisms of vitiligo development and… read more here.
Keywords: etiology; immunometabolism pathogenesis; immunometabolism; pathogenesis vitiligo ... See more keywords
Immunometabolism – The Role of Branched-Chain Amino Acids
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.886822
Abstract: Immunometabolism has been the focus of extensive research over the last years, especially in terms of augmenting anti-tumor immune responses. Regulatory T cells (Tregs) are a subset of CD4+ T cells, which have been known… read more here.
Keywords: amino acids; chain amino; immunometabolism; branched chain ... See more keywords
B cell activation via immunometabolism in systemic lupus erythematosus
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1155421
Abstract: Systemic lupus erythematosus (SLE) is an inflammatory autoimmune disease involving multiple organs in which B cells perform important functions such as antibody and cytokine production and antigen presentation. B cells are activated and differentiated by… read more here.
Keywords: lupus erythematosus; systemic lupus; activation; immunometabolism ... See more keywords