An immunometabolism‐related signature for renal clear cell carcinoma diagnosis and therapeutic target
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Cell Communication and Signaling"
DOI: 10.1002/ccs3.70047
Abstract: Kidney renal clear cell carcinoma (KIRC) lacks sensitive early diagnostic markers and effective therapeutic guidance. Given the tight crosstalk between tumor metabolism and immunity, we investigated immunometabolism for biomarker discovery. Transcriptomes from The Cancer Genome… read more here.
Keywords: immunometabolism; renal clear; cell; cell carcinoma ... See more keywords
Immunometabolism: Another Road to Sepsis and Its Therapeutic Targeting
Sign Up to like & getrecommendations! Published in 2018 at "Inflammation"
DOI: 10.1007/s10753-018-0939-8
Abstract: Sepsis is a major health problem all over the world. Despite its existence since the time of Hippocrates (470 BC), sepsis is still a serious medical problem for physicians working in both pediatric and adult intensive… read more here.
Keywords: sepsis; immunometabolism; road sepsis; another road ... See more keywords
An Integrated View of Immunometabolism
Sign Up to like & getrecommendations! Published in 2018 at "Cell"
DOI: 10.1016/j.cell.2017.12.025
Abstract: The worldwide obesity epidemic has emerged as a major cause of insulin resistance and Type 2 diabetes. Chronic tissue inflammation is a well-recognized feature of obesity, and the field of immunometabolism has witnessed many advances… read more here.
Keywords: view immunometabolism; immunometabolism; insulin; inflammation ... See more keywords
Triclosan Reprograms Immunometabolism and Activates the Inflammasome in Human Macrophages.
Sign Up to like & getrecommendations! Published in 2022 at "Environmental science & technology"
DOI: 10.1021/acs.est.2c05254
Abstract: To gather enough energy to respond to harmful stimuli, most immune cells quickly shift their metabolic profile. This process of immunometabolism plays a critical role in the regulation of immune cell function. Triclosan, a synthetic… read more here.
Keywords: immunometabolism; triclosan reprograms; immunometabolism activates; reprograms immunometabolism ... See more keywords
Immunometabolism in cancer: basic mechanisms and new targeting strategy
Sign Up to like & getrecommendations! Published in 2024 at "Cell Death Discovery"
DOI: 10.1038/s41420-024-02006-2
Abstract: Maturing immunometabolic research empowers immune regulation novel approaches. Progressive metabolic adaptation of tumor cells permits a thriving tumor microenvironment (TME) in which immune cells always lose the initial killing capacity, which remains an unsolved dilemma… read more here.
Keywords: immunometabolism; cancer; immunity; catabolism ... See more keywords
Pathogenesis of ANCA-associated vasculitis: an emerging role for immunometabolism.
Sign Up to like & getrecommendations! Published in 2020 at "Rheumatology"
DOI: 10.1093/rheumatology/keaa023
Abstract: ANCA-associated vasculitis (AAV) is a severe systemic autoimmune disease. A key feature of AAV is the presence of Anti-Neutrophil Cytoplasmic Antibodies (ANCA) directed against myeloperoxidase (MPO) or proteinase-3 (PR3). ANCA are key to the pathogenesis… read more here.
Keywords: immunometabolism; immune cell; pathogenesis; associated vasculitis ... See more keywords
Immunometabolism shapes B cell fate and functions
Sign Up to like & getrecommendations! Published in 2022 at "Immunology"
DOI: 10.1111/imm.13499
Abstract: B lymphocyte‐mediated humoral immune response is essential for protection against infectious diseases. Deeper research in B cell biology, particularly metabolism is required for the better understanding of its properties in homeostasis and in diseases. Emerging… read more here.
Keywords: cell fate; cell; metabolism; development ... See more keywords
Immunometabolism: From basic mechanisms to translation
Sign Up to like & getrecommendations! Published in 2020 at "Immunological Reviews"
DOI: 10.1111/imr.12858
Abstract: Immunometabolism has emerged as a major mechanism central to adaptive and innate immune regulation. From early observations that inflammatory cytokines were induced in obese adipose tissue and that these cytokines contributed to metabolic disease, it… read more here.
Keywords: basic mechanisms; immunometabolism; mechanisms translation; translation ... See more keywords
Intracellular and Intercellular Aspects of Macrophage Immunometabolism in Atherosclerosis.
Sign Up to like & getrecommendations! Published in 2020 at "Circulation research"
DOI: 10.1161/circresaha.119.315939
Abstract: Macrophage immunometabolism, the changes in intracellular metabolic pathways that alter the function of these highly plastic cells, has been the subject of intense interest in the past few years, in part because macrophage immunometabolism plays… read more here.
Keywords: immunometabolism atherosclerosis; aspects macrophage; macrophage immunometabolism; immunometabolism ... See more keywords
Bridging epigenomics and tumor immunometabolism: molecular mechanisms and therapeutic implications
Sign Up to like & getrecommendations! Published in 2025 at "Molecular Cancer"
DOI: 10.1186/s12943-025-02269-y
Abstract: Epigenomic modifications—such as DNA methylation, histone acetylation, and histone methylation—and their implications in tumorigenesis, progression, and treatment have emerged as a pivotal field in cancer research. Tumors undergo metabolic reprogramming to sustain proliferation and metastasis… read more here.
Keywords: immunometabolism; epigenomics tumor; immunometabolism molecular; tumor ... See more keywords
Similarities and Distinctions in the Effects of Metformin and Carbon Monoxide in Immunometabolism
Sign Up to like & getrecommendations! Published in 2019 at "Molecules and Cells"
DOI: 10.14348/molcells.2019.0016
Abstract: Immunometabolism, defined as the interaction of metabolic pathways with the immune system, influences the pathogenesis of metabolic diseases. Metformin and carbon monoxide (CO) are two pharmacological agents known to ameliorate metabolic disorders. There are notable… read more here.
Keywords: immunometabolism; metformin carbon; carbon monoxide; effects metformin ... See more keywords