Controlled Delivery of Immunomodulatory Factors for Mineralized Tissue Formation in an Inflammatory Microenvironment.
Sign Up to like & getrecommendations! Published in 2025 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202502466
Abstract: Mesenchymal stromal cells (MSCs) are a promising cell-based therapy for bone healing, contributing to tissue regeneration through direct differentiation or immunomodulatory factor secretion. However, diseases that feature chronic or dysregulated inflammation, such as non-union fractures… read more here.
Keywords: immunomodulatory factors; delivery immunomodulatory; immunomodulatory; controlled delivery ... See more keywords
A “Mesoporous Oxygen Chamber” Scaffold with Antibacterial and Early Immunomodulatory Effect for Promoting Bone Regeneration
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202506737
Abstract: Regeneration of bone defects are frequently hindered by severe inflammation, immunogenicity after bone repairing material implantation, and microbial infections. Oxygen therapy is reported to downregulate the levels of pro‐inflammatory cytokines and proteases, alleviating inflammation and… read more here.
Keywords: oxygen; delivery; bone regeneration; immunomodulatory ... See more keywords
Varicella‐zoster virus‐related neurological complications: From infection to immunomodulatory therapies
Sign Up to like & getrecommendations! Published in 2024 at "Reviews in Medical Virology"
DOI: 10.1002/rmv.2554
Abstract: The Varicella‐zoster virus (VZV), classified as a neurotropic member of the Herpesviridae family, exhibits a characteristic pathogenicity, predominantly inducing varicella, commonly known as chickenpox, during the initial infectious phase, and triggering the reactivation of herpes… read more here.
Keywords: vzv; varicella zoster; zoster virus; immunomodulatory ... See more keywords
Controlled aggregation enhances immunomodulatory potential of mesenchymal stromal cell aggregates
Sign Up to like & getrecommendations! Published in 2021 at "Stem Cells Translational Medicine"
DOI: 10.1002/sctm.19-0414
Abstract: Human mesenchymal stromal cells (MSCs) are promising candidates for cell therapy due to their ease of isolation and expansion and their ability to secrete antiapoptotic, pro‐angiogenic, and immunomodulatory factors. Three‐dimensional (3D) aggregation “self‐activates” MSCs to… read more here.
Keywords: aggregation; mesenchymal stromal; immunomodulatory potential; immunomodulatory ... See more keywords
Immunomodulatory and cardio-protective effects of differentially originated multipotent mesenchymal stroma cells during polymicrobial sepsis in mice
Sign Up to like & getrecommendations! Published in 2025 at "European Journal of Trauma and Emergency Surgery"
DOI: 10.1007/s00068-025-02862-2
Abstract: Sepsis is a life-threatening condition with cardiac complications being an independent predictor of poor outcome. Although their mechanisms have been widely investigated, therapeutic options remain limited. One promising therapeutic tool are mesenchymal stromal cells (MSCs).… read more here.
Keywords: mice; polymicrobial sepsis; immunomodulatory; bmmsc ... See more keywords
Identification of immunomodulatory peptides from zein hydrolysates
Sign Up to like & getrecommendations! Published in 2020 at "European Food Research and Technology"
DOI: 10.1007/s00217-020-03450-x
Abstract: Food protein-derived bioactive peptides have been recognized as a promising candidate for the development of functional foods or nutraceuticals. Peptides exhibiting antioxidant, anti-proliferative and anti-hypertensive activities have been characterized from corn proteins while the knowledge… read more here.
Keywords: immunomodulatory peptides; zein hydrolysates; identification immunomodulatory; immunomodulatory ... See more keywords
Immunomodulatory activities of zinc(II)phthalocyanine on the mammalian macrophages through p38 pathway: Potential ex vivo immunomodulatory PDT reagents.
Sign Up to like & getrecommendations! Published in 2019 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2019.103249
Abstract: A series of zinc phthalocyanine having imidazolyl moieties was synthesized. These compounds' immunostimulatory and immunomodulatory activities were tested on the mammalian macrophages in vitro. In the absence of photo induction neither dmso soluble nor the… read more here.
Keywords: immunomodulatory activities; activities zinc; immunomodulatory; mammalian macrophages ... See more keywords
Purification, characterization and immunomodulatory activity of fructans from Polygonatum odoratum and P. cyrtonema.
Sign Up to like & getrecommendations! Published in 2019 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2019.03.014
Abstract: Two neutral polysaccharides named POP-1 and PCP-1 were purified from Polygonatum odoratum and P. cyrtonema, respectively. Results showed that both of them were composed of fructose and glucose, and the average molecular weights of them… read more here.
Keywords: immunomodulatory; odoratum cyrtonema; activity; polygonatum odoratum ... See more keywords
Mining the Human Gut Microbiota for Immunomodulatory Organisms
Sign Up to like & getrecommendations! Published in 2017 at "Cell"
DOI: 10.1016/j.cell.2017.01.022
Abstract: Within the human gut reside diverse microbes coexisting with the host in a mutually advantageous relationship. Evidence has revealed the pivotal role of the gut microbiota in shaping the immune system. To date, only a… read more here.
Keywords: gut; mining human; human gut; immunomodulatory ... See more keywords
Intravesical Immunomodulatory Imiquimod Enhances Bacillus Calmette‐Guérin Downregulation of Nonmuscle‐invasive Bladder Cancer
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Genitourinary Cancer"
DOI: 10.1016/j.clgc.2017.10.019
Abstract: &NA; The Toll‐like receptor (TLR)2/4 agonist bacillus Calmette‐Guérin (BCG) is the most efficient immunomodulatory treatment of nonmuscle‐invasive bladder cancer (NMIBC). BCG modulation by the TLR7 agonist imiquimod was evaluated in an immunocompetent animal model. We… read more here.
Keywords: bladder; histopathology; immunomodulatory; cancer ... See more keywords
Immunomodulatory therapy, risk factors and outcomes of hospital-acquired bloodstream infection in patients with severe COVID-19 pneumonia: a Spanish case–control matched multicentre study (BACTCOVID)
Sign Up to like & getrecommendations! Published in 2021 at "Clinical Microbiology and Infection"
DOI: 10.1016/j.cmi.2021.06.041
Abstract: Objectives The effect of the use of immunomodulatory drugs on the risk of developing hospital-acquired bloodstream infection (BSI) in patients with COVID-19 has not been specifically assessed. We aim to identify risk factors for, and… read more here.
Keywords: risk; patients severe; infection; immunomodulatory ... See more keywords