Controlled aggregation enhances immunomodulatory potential of mesenchymal stromal cell aggregates
Sign Up to like & getrecommendations! Published in 2021 at "Stem Cells Translational Medicine"
DOI: 10.1002/sctm.19-0414
Abstract: Human mesenchymal stromal cells (MSCs) are promising candidates for cell therapy due to their ease of isolation and expansion and their ability to secrete antiapoptotic, pro‐angiogenic, and immunomodulatory factors. Three‐dimensional (3D) aggregation “self‐activates” MSCs to… read more here.
Keywords: aggregation; mesenchymal stromal; immunomodulatory potential; immunomodulatory ... See more keywords
Identification of immunomodulatory peptides from zein hydrolysates
Sign Up to like & getrecommendations! Published in 2020 at "European Food Research and Technology"
DOI: 10.1007/s00217-020-03450-x
Abstract: Food protein-derived bioactive peptides have been recognized as a promising candidate for the development of functional foods or nutraceuticals. Peptides exhibiting antioxidant, anti-proliferative and anti-hypertensive activities have been characterized from corn proteins while the knowledge… read more here.
Keywords: immunomodulatory peptides; zein hydrolysates; identification immunomodulatory; immunomodulatory ... See more keywords
Immunomodulatory activities of zinc(II)phthalocyanine on the mammalian macrophages through p38 pathway: Potential ex vivo immunomodulatory PDT reagents.
Sign Up to like & getrecommendations! Published in 2019 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2019.103249
Abstract: A series of zinc phthalocyanine having imidazolyl moieties was synthesized. These compounds' immunostimulatory and immunomodulatory activities were tested on the mammalian macrophages in vitro. In the absence of photo induction neither dmso soluble nor the… read more here.
Keywords: immunomodulatory activities; activities zinc; immunomodulatory; mammalian macrophages ... See more keywords
Purification, characterization and immunomodulatory activity of fructans from Polygonatum odoratum and P. cyrtonema.
Sign Up to like & getrecommendations! Published in 2019 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2019.03.014
Abstract: Two neutral polysaccharides named POP-1 and PCP-1 were purified from Polygonatum odoratum and P. cyrtonema, respectively. Results showed that both of them were composed of fructose and glucose, and the average molecular weights of them… read more here.
Keywords: immunomodulatory; odoratum cyrtonema; activity; polygonatum odoratum ... See more keywords
Mining the Human Gut Microbiota for Immunomodulatory Organisms
Sign Up to like & getrecommendations! Published in 2017 at "Cell"
DOI: 10.1016/j.cell.2017.01.022
Abstract: Within the human gut reside diverse microbes coexisting with the host in a mutually advantageous relationship. Evidence has revealed the pivotal role of the gut microbiota in shaping the immune system. To date, only a… read more here.
Keywords: gut; mining human; human gut; immunomodulatory ... See more keywords
Intravesical Immunomodulatory Imiquimod Enhances Bacillus Calmette‐Guérin Downregulation of Nonmuscle‐invasive Bladder Cancer
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Genitourinary Cancer"
DOI: 10.1016/j.clgc.2017.10.019
Abstract: &NA; The Toll‐like receptor (TLR)2/4 agonist bacillus Calmette‐Guérin (BCG) is the most efficient immunomodulatory treatment of nonmuscle‐invasive bladder cancer (NMIBC). BCG modulation by the TLR7 agonist imiquimod was evaluated in an immunocompetent animal model. We… read more here.
Keywords: bladder; histopathology; immunomodulatory; cancer ... See more keywords
Immunomodulatory therapy, risk factors and outcomes of hospital-acquired bloodstream infection in patients with severe COVID-19 pneumonia: a Spanish case–control matched multicentre study (BACTCOVID)
Sign Up to like & getrecommendations! Published in 2021 at "Clinical Microbiology and Infection"
DOI: 10.1016/j.cmi.2021.06.041
Abstract: Objectives The effect of the use of immunomodulatory drugs on the risk of developing hospital-acquired bloodstream infection (BSI) in patients with COVID-19 has not been specifically assessed. We aim to identify risk factors for, and… read more here.
Keywords: risk; patients severe; infection; immunomodulatory ... See more keywords
Immunomodulatory effect of natural and modified citrus pectin on cytokines levels in the spleen of BALB/c mice.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2018.09.189
Abstract: Pectin is present in the cell wall of different vegetables and fruits. Beside its importance in the plant cell wall, pectin has enticed great attention for its beneficial effects on human health. It was shown… read more here.
Keywords: modified citrus; citrus pectin; pectin; immunomodulatory ... See more keywords
Structural characterization, antioxidant activity, and immunomodulatory activity of non-starch polysaccharides from Chuanminshen violaceum collected from different regions.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2019.09.151
Abstract: Chuanminshen violaceum has been used as an important traditional Chinese medicine and a popular tonic food in China. Polysaccharides are considered the major bioactive components in C. violaceum. In this study, in order well understand… read more here.
Keywords: violaceum collected; different regions; collected different; immunomodulatory ... See more keywords
Development of a flow cytometry assay which allows to evaluate the efficiency of immunomodulatory vaccines to enhance T cell-mediated antitumor response.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of biotechnology"
DOI: 10.1016/j.jbiotec.2018.07.029
Abstract: Immunotherapy has revolutionized the treatment of cancer. Since tumor cells exhibit low immunogenicity and can induce several mechanisms of tolerance, the use of monoclonal antibodies or other immunomodulators, targeting costimulation of T cells may mediate… read more here.
Keywords: response; immunomodulatory; flow cytometry; development ... See more keywords
Melatonin Treatment Alters Biological and Immunomodulatory Properties of Human Dental Pulp Mesenchymal Stem Cells Via Augmented TGFβ Secretion.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of endodontics"
DOI: 10.1016/j.joen.2020.12.008
Abstract: INTRODUCTION Melatonin is an endogenous neurohormone with well-reported anti-inflammatory and anti-oxidant properties, but the direct biological and immunomodulatory effects of melatonin on human dental pulp stem cells (hDPSCs) has not been fully elucidated. AIM To… read more here.
Keywords: immunomodulatory properties; immunomodulatory; melatonin treatment; melatonin ... See more keywords