TGFβ1 transduction enhances immunomodulatory capacity of neural stem cells in experimental autoimmune encephalomyelitis
Sign Up to like & getrecommendations! Published in 2018 at "Brain, Behavior, and Immunity"
DOI: 10.1016/j.bbi.2017.11.023
Abstract: Bone marrow-derived neural stem cells (BM-NSCs) have therapeutic effect on EAE, an animal model of multiple sclerosis. However, the beneficial effect is suboptimal due to the limited immunomodulatory capacity of these cells. In this study,… read more here.
Keywords: capacity; immunomodulatory capacity; tgf; stem cells ... See more keywords
Mesenchymal stem cells derived from human inflamed dental pulp exhibit impaired immunomodulatory capacity in vitro.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of endodontics"
DOI: 10.1016/j.joen.2020.05.003
Abstract: Abstract Introduction Dental pulp stem cells (DPSC) are very attractive in regenerative medicine. In this study, we focused on the characterization of the functional properties of mesenchymal stem cells derived from DPSCs. Currently, it is… read more here.
Keywords: immunomodulatory capacity; dental pulp; inflamed dental; stem cells ... See more keywords
Immunomodulatory capacity of the serotonin receptor 5-HT2B in a subset of human dendritic cells
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-20173-y
Abstract: Serotonin is a monoamine neurotransmitter that signals through a wide array of receptors (5-HT1–7) many of which are also involved in immune processes. Dendritic cells (DCs) are crucial players in immune defense by bridging innate… read more here.
Keywords: immunomodulatory capacity; ht2b; serotonin; dendritic cells ... See more keywords
IDO and CD40 May Be Key Molecules for Immunomodulatory Capacity of the Primed Tonsil-Derived Mesenchymal Stem Cells
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22115772
Abstract: Background: Tonsil-derived mesenchymal stem cells (T-MSCs) were reported to have suppressive effect on T cells, yet much remains unknown about the underlying mechanisms supporting this effect. We investigated the underlying mechanism of the immunomodulatory effect… read more here.
Keywords: ido cd40; immunomodulatory capacity; cd40; effect ... See more keywords