Immunomodulatory Effects of Lenvatinib Plus Anti–Programmed Cell Death Protein 1 in Mice and Rationale for Patient Enrichment in Hepatocellular Carcinoma
Sign Up to like & getrecommendations! Published in 2021 at "Hepatology"
DOI: 10.1002/hep.32023
Abstract: Lenvatinib is an effective drug in advanced HCC. Its combination with the anti‐PD1 (programmed cell death protein 1) immune checkpoint inhibitor, pembrolizumab, has generated encouraging results in phase Ib and is currently being tested in… read more here.
Keywords: death protein; immunomodulatory effects; programmed cell; cell death ... See more keywords
A phase 1b study of OXIRI in pancreatic adenocarcinoma patients and its immunomodulatory effects
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Cancer"
DOI: 10.1002/ijc.34021
Abstract: Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal and debilitating disease with limited therapeutic options. The aim of this clinical study was to evaluate the safety, efficacy and pharmacokinetics of a novel regimen comprised of… read more here.
Keywords: immunomodulatory effects; study oxiri; phase study; adenocarcinoma ... See more keywords
Polarized light therapy: Shining a light on the mechanism underlying its immunomodulatory effects
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Biophotonics"
DOI: 10.1002/jbio.201960177
Abstract: Abstract This study investigates the immunomodulatory effects of polychromatic polarized light therapy (PLT) on human monocyte cells. While there is some evidence demonstrating a clinical effect in the treatment of certain conditions, there is little… read more here.
Keywords: therapy shining; polarized light; mechanism; immunomodulatory effects ... See more keywords
Immunomodulatory effects of curcumin in systemic autoimmune diseases
Sign Up to like & getrecommendations! Published in 2022 at "Phytotherapy Research"
DOI: 10.1002/ptr.7417
Abstract: Systemic autoimmune diseases like rheumatoid arthritis, multiple sclerosis, and systemic lupus erythematosus represent various autoimmune conditions identified by immune system dysregulation. The activation of immune cells, auto‐antigen outbreak, inflammation, and multi‐organ impairment is observed in… read more here.
Keywords: autoimmune diseases; systemic autoimmune; curcumin systemic; immunomodulatory effects ... See more keywords
Randomized controlled trial on immunomodulatory effects of azithromycin in children with steroid-dependent nephrotic syndrome
Sign Up to like & getrecommendations! Published in 2019 at "Pediatric Nephrology"
DOI: 10.1007/s00467-019-04251-5
Abstract: BackgroundAzithromycin (AZM) is a macrolide antibiotic with anti-inflammatory and immunomodulatory effects. Our aim was to compare the immunomodulatory effects of AZM combined with steroid therapy with that of steroid therapy alone in children with steroid-dependent… read more here.
Keywords: children steroid; group; dependent nephrotic; immunomodulatory effects ... See more keywords
Immunomodulatory effects of Rhodomyrtus tomentosa leaf extract and its derivative compound, rhodomyrtone, on head kidney macrophages of rainbow trout (Oncorhynchus mykiss)
Sign Up to like & getrecommendations! Published in 2017 at "Fish Physiology and Biochemistry"
DOI: 10.1007/s10695-017-0452-2
Abstract: Rhodomyrtus tomentosa is a medicinal plant that shows biological effects including immunomodulatory activity on human and other mammals but not in fish. In this study, we evaluated the in vitro immunomodulatory effects of R. tomentosa… read more here.
Keywords: rhodomyrtus tomentosa; tomentosa leaf; leaf extract; rhodomyrtone ... See more keywords
Ex Vivo Immunomodulatory Effects of Lactobacillus-, Lacticaseibacillus-, and Bifidobacterium-Containing Synbiotics on Human Peripheral Blood Mononuclear Cells and Monocyte-Derived Dendritic Cells in the Context of Grass Pollen Allergy
Sign Up to like & getrecommendations! Published in 2022 at "Probiotics and Antimicrobial Proteins"
DOI: 10.1007/s12602-022-09920-w
Abstract: Sensing of the intestinal microbiota by the host immune system is important to induce protective immune responses. Hence, modification of the gut microbiota might be able to prevent or treat allergies, mediated by proinflammatory Th2… read more here.
Keywords: grass pollen; gpe; vivo immunomodulatory; grass ... See more keywords
Immunomodulatory effects of polysaccharide fraction isolated from Fagopyrum esculentum on innate immune system.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.01.172
Abstract: The present study investigates the immunomodulatory activities of buckwheat polysaccharide fraction (BPF) from the seed of Fagopyrum esculentum on RAW 264.7 macrophage cell line and Cyclophosphamide-induced immunosuppressed conditions in mice models. The results of in vitro… read more here.
Keywords: immune; fagopyrum esculentum; immunomodulatory effects; polysaccharide fraction ... See more keywords
Immunomodulatory effects of xanthan gum in LPS-stimulated RAW 264.7 macrophages.
Sign Up to like & getrecommendations! Published in 2017 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2017.04.003
Abstract: In this study, we evaluated the immunomodulatory effects of xanthan gum (XG) in RAW264.7 macrophages and the underlying molecular mechanisms. We used scanning electron microscopy (SEM) to analyze the morphology of XG-treated RAW264.7 cells with… read more here.
Keywords: raw264 macrophages; lps stimulated; immunomodulatory effects; xanthan gum ... See more keywords
Lupeol and amphotericin B mediate synergistic anti-leishmanial immunomodulatory effects in Leishmania donovani-infected BALB/c mice.
Sign Up to like & getrecommendations! Published in 2020 at "Cytokine"
DOI: 10.1016/j.cyto.2020.155319
Abstract: Leishmania donovani, a protozoan parasite, inflicts the disease Visceral leishmaniasis (VL) Worldwide. The only orally bioavailable drug miltefosine is toxic, whereas liposomal amphotericin B (AmpB) is expensive. Lupeol, a triterpenoid from Sterculia villosa bark, was… read more here.
Keywords: leishmanial immunomodulatory; anti leishmanial; lupeol; immunomodulatory effects ... See more keywords
Immunomodulatory effects of the polysaccharide from Craterellus cornucopioides via activating the TLR4-NFκB signaling pathway in peritoneal macrophages of BALB/c mice.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2020.05.270
Abstract: The immunoregulatory effect and immunologic response mechanism of Craterellus cornucopioides (L.) Pers. polysaccharide (CCP) with a triple-helix structure on peritoneal macrophages was investigated in vitro for the first time. These studies demonstrated that treatment of… read more here.
Keywords: craterellus cornucopioides; peritoneal macrophages; immunomodulatory effects; peritoneal ... See more keywords