Silk fibroin scaffolds potentiate immunomodulatory function of human mesenchymal stromal cells.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.09.006
Abstract: Although mesenchymal stromal cells (MSCs) show great potential for use in regenerative medicine, their therapeutic efficacy remains limited because of their low adaptation efficiency and viability observed in clinical trials. To potentiate the adaptation and… read more here.
Keywords: mesenchymal stromal; stromal cells; silk fibroin; sfn sheets ... See more keywords
Evaluation of Porcine Versus Human Mesenchymal Stromal Cells From Three Distinct Donor Locations for Cytotherapy
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2020.00826
Abstract: Background: Mesenchymal stromal cell (MSC)-based cytotherapies fuel the hope for reduction of chronic systemic immunosuppression in allotransplantation, and our group has previously shown this capability for both swine and human cells. MSCs harvested from distinct… read more here.
Keywords: mesenchymal stromal; porcine; immunomodulatory function; mscs ... See more keywords
Improving the immunomodulatory function of mesenchymal stem cells by defined chemical approach
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1005426
Abstract: Mesenchymal stem cell (MSC) is a potential therapeutic material that has self-renewal, multilineage differentiation, and immunomodulation properties. However, the biological function of MSCs may decline due to the influence of donor differences and the in… read more here.
Keywords: function; improving immunomodulatory; immunomodulatory function; mesenchymal stem ... See more keywords
The immunomodulatory function of adenosine in sepsis
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DOI: 10.3389/fimmu.2022.936547
Abstract: Sepsis is an unsolved clinical condition with a substantial mortality rate in the hospital. Despite decades of research, no effective treatments for sepsis exists. The role of adenosine in the pathogenesis of sepsis is discussed… read more here.
Keywords: sepsis; function adenosine; adenosine; immunomodulatory function ... See more keywords
Immunomodulatory function and anti-tumor mechanism of natural polysaccharides: A review
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1147641
Abstract: Polysaccharides extracted from natural resources have attracted extensive attention in biomedical research and pharmaceutical fields, due to their medical values in anti-tumor, immunomodulation, drug delivery, and many other aspects. At present, a variety of natural… read more here.
Keywords: natural polysaccharides; anti tumor; function anti; immunomodulatory function ... See more keywords