Controlled aggregation enhances immunomodulatory potential of mesenchymal stromal cell aggregates
Sign Up to like & getrecommendations! Published in 2021 at "Stem Cells Translational Medicine"
DOI: 10.1002/sctm.19-0414
Abstract: Human mesenchymal stromal cells (MSCs) are promising candidates for cell therapy due to their ease of isolation and expansion and their ability to secrete antiapoptotic, pro‐angiogenic, and immunomodulatory factors. Three‐dimensional (3D) aggregation “self‐activates” MSCs to… read more here.
Keywords: aggregation; mesenchymal stromal; immunomodulatory potential; immunomodulatory ... See more keywords
The Immunomodulatory Potential of the Metabolite Itaconate.
Sign Up to like & getrecommendations! Published in 2019 at "Trends in immunology"
DOI: 10.1016/j.it.2019.05.007
Abstract: The field of immunometabolism has demonstrated that metabolites can lead double lives as immunomodulators. Itaconate is perhaps the best example of such a moonlighting molecule, and has been shown to have multiple anti-inflammatory effects in… read more here.
Keywords: metabolite itaconate; immunomodulatory potential; potential metabolite;
Human Articular Chondrocytes Retain Their Phenotype in Sustained Hypoxia While Normoxia Promotes Their Immunomodulatory Potential
Sign Up to like & getrecommendations! Published in 2018 at "Cartilage"
DOI: 10.1177/1947603518769714
Abstract: Objective To assess the phenotype of human articular chondrocytes cultured in normoxia (21% O2) or continuous hypoxia (2% O2). Design Chondrocytes were extracted from patients undergoing total knee replacement (n = 5) and cultured in… read more here.
Keywords: phenotype; normoxia promotes; immunomodulatory potential; chondrogenic potency ... See more keywords
Bifidobacterium longum Ameliorates Ovariectomy-Induced Bone Loss via Enhancing Anti-Osteoclastogenic and Immunomodulatory Potential of Regulatory B Cells (Bregs)
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.875788
Abstract: Discoveries in the last few years have emphasized the existence of an enormous breadth of communication between osteo-immune systems. These discoveries fuel novel approaches for the treatment of several bone pathologies including osteoporosis. Bifidobacterium longum… read more here.
Keywords: bone; immunomodulatory potential; bifidobacterium longum; anti osteoclastogenic ... See more keywords
Immunomodulatory Potential of Non-Classical HLA-G in Infections including COVID-19 and Parasitic Diseases
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12020257
Abstract: Human Leukocyte Antigen-G (HLA-G), a polymorphic non-classical HLA (HLA-Ib) with immune-regulatory properties in cancers and infectious diseases, presents both membrane-bound and soluble (sHLA-G) isoforms. Polymorphism has implications in host responses to pathogen infections and in… read more here.
Keywords: hla; potential non; immunomodulatory potential; classical hla ... See more keywords
Immunomodulatory Potential of the Industrialized Houttuynia cordata Fermentation Product In Vitro and in Wistar Rats
Sign Up to like & getrecommendations! Published in 2021 at "Foods"
DOI: 10.3390/foods10112582
Abstract: Houttuynia cordata fermentation products (HCFPs) are produced and widely used as dietary supplements for health and immune support. However, the effect on immune function for these products has not been clearly demonstrated. In this study,… read more here.
Keywords: selected hcfp; houttuynia cordata; cordata fermentation; immunomodulatory potential ... See more keywords
Immunoceuticals: Harnessing Their Immunomodulatory Potential to Promote Health and Wellness
Sign Up to like & getrecommendations! Published in 2022 at "Nutrients"
DOI: 10.3390/nu14194075
Abstract: Knowledge that certain nutraceuticals can modulate the immune system is not new. These naturally occurring compounds are known as immunoceuticals, which is a novel term that refers to products and systems that naturally improve an… read more here.
Keywords: system; immunomodulatory potential; immunoceuticals harnessing; harnessing immunomodulatory ... See more keywords
Antioxidant, Immunomodulatory and Potential Anticancer Capacity of Polysaccharides (Glucans) from Euglena gracilis G.A. Klebs
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DOI: 10.3390/ph15111379
Abstract: The present study was carried out to determine the bioactivity of polysaccharides extracted from Euglena gracilis (EgPs). These were characterized by FT-IR and GC-MS. Cytotoxicity analyses (MTT) were performed on healthy human gingival fibroblast cell… read more here.
Keywords: immunomodulatory potential; capacity; antioxidant immunomodulatory; anticancer ... See more keywords
Immunomodulatory potential of anticancer therapy composed of methotrexate nanoconjugate and dendritic cell-based vaccines in murine colon carcinoma
Sign Up to like & getrecommendations! Published in 2021 at "Oncology Reports"
DOI: 10.3892/or.2021.7930
Abstract: Chemotherapy with low-molecular weight compounds, despite elimination of cancer cells, entails adverse effects. To overcome this disadvantage, innovative drug delivery systems are being developed, including conjugation of macromolecular carriers with therapeutics, e.g. a nanoconjugate of… read more here.
Keywords: response; based vaccines; treatment; immunomodulatory potential ... See more keywords