Articles with "immunopeptidomic profiling" as a keyword



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Physical and in silico immunopeptidomic profiling of a cancer antigen prostatic acid phosphatase reveals targets enabling TCR isolation

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Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.2203410119

Abstract: Significance Interaction between peptide–major histocompatibility complexes (pMHCs) and T cell receptors (TCRs) is the key mediator for tumor cell recognition by cytotoxic T cells. We performed a multimodal analysis on a prostate tissue antigen, PAP,… read more here.

Keywords: silico immunopeptidomic; cancer; immunopeptidomic profiling; physical silico ... See more keywords