Development of mutant human immunoreactive trypsinogen 1 (IRT1) and mutant human immunoreactive trypsinogen 2 (IRT2) for use in immunoassays.
Sign Up to like & getrecommendations! Published in 2020 at "Protein expression and purification"
DOI: 10.1016/j.pep.2020.105572
Abstract: Immunoreactive Trypsinogen (IRT) is a protein-based pancreatic proenzyme that has an important role in protein digestion in humans. In human body, once IRT present in the small intestine, the proteolytic cleavage activates trypsinogen into trypsin.… read more here.
Keywords: immunoreactive trypsinogen; human immunoreactive; mutant human; trypsinogen irt1 ... See more keywords
Immunoreactive trypsinogen in healthy newborns and infants with cystic fibrosis
Sign Up to like & getrecommendations! Published in 2022 at "Archives of Disease in Childhood"
DOI: 10.1136/archdischild-2021-323549
Abstract: Objective Newborn screening (NBS) for cystic fibrosis (CF) was introduced in Switzerland in 2011 based on an immunoreactive trypsinogen (IRT)-DNA-IRT protocol. CF diagnosis was confirmed by sweat test and/or genetics but remained inconclusive for some… read more here.
Keywords: healthy newborns; irt; immunoreactive trypsinogen; cystic fibrosis ... See more keywords