The structural basis for membrane assembly of immunoreceptor signalling complexes
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Molecular Modeling"
DOI: 10.1007/s00894-019-4165-6
Abstract: Immunoreceptors are TM complexes that consist of separate ligand-binding and signal-transducing modules. Mounting evidence suggests that interactions with the local environment may influence the architecture of these TM domains, which assemble via crucial sets of… read more here.
Keywords: structural basis; membrane assembly; basis membrane; immunoreceptor ... See more keywords
CD155 mutation (Ala67Thr) increases the binding affinity for and the signaling via an inhibitory immunoreceptor TIGIT
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DOI: 10.1111/cas.15526
Abstract: CD155 is a shared ligand for activating and inhibitory immunoreceptors DNAX accessory molecule 1 (DNAM‐1), also called CD226, and T cell immunoglobulin and immunoreceptor tyrosine‐based inhibitory motif domain (TIGIT), which are expressed on natural killer… read more here.
Keywords: binding affinity; tigit; immunoreceptor; mutation ... See more keywords
Astrocytic Expression of the Immunoreceptor CD300f Protects Hippocampal Neurons from Amyloid-β Oligomer Toxicity In Vitro.
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DOI: 10.2174/1567205014666170202121709
Abstract: BACKGROUND Astrocytes contribute to neuroinflammation that accompanies neurodegenerative disorders such as Alzheimer's disease (AD). In this sense, the toxicity of these diseases might be attenuated through the modulation of astrocytic inflammatory responses. Recently, the CD300f… read more here.
Keywords: hippocampal neurons; protects hippocampal; immunoreceptor; toxicity ... See more keywords