The intragraft microenvironment as a central determinant of chronic rejection or local immunoregulation/tolerance
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DOI: 10.1097/mot.0000000000000373
Abstract: Purpose of review Chronic rejection is associated with persistent mononuclear cell recruitment, endothelial activation and proliferation, local tissue hypoxia and related biology that enhance effector immune responses. In contrast, the tumor microenvironment elicits signals/factors that… read more here.
Keywords: immunoregulation; tolerance; rejection; chronic rejection ... See more keywords
Psoriatic Serum Induce an Abnormal Inflammatory Phenotype and a Decreased Immunosuppressive Function of Mesenchymal Stem Cells
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DOI: 10.15283/ijsc20210
Abstract: Background and Objectives Mesenchymal stem cells (MSCs) have immunomodulatory function and participate in the pathogenesis of many immunoregulation-related diseases, including psoriasis. Previously, we found that MSCs from psoriatic lesions overexpress the proinflammatory microRNA, miR-155 and… read more here.
Keywords: function; serum; immunoregulation; psoriatic serum ... See more keywords