Articles with "immunosenescence" as a keyword



Photo from wikipedia

Perspectives on the dynamic implications of cellular senescence and immunosenescence on macrophage aging biology.

Sign Up to like & get
recommendations!
Published in 2021 at "Biogerontology"

DOI: 10.1007/s10522-021-09936-9

Abstract: An intricate relationship between impaired immune functions and the age-related accumulation of tissue senescent cells is rapidly emerging. The immune system is unique as it undergoes mutually inclusive and deleterious processes of immunosenescence and cellular… read more here.

Keywords: senescence; immunosenescence; biology; macrophage ... See more keywords
Photo by johnarano from unsplash

Voluntary exercise reverses immune aging induced by oxidative stress in aging mice

Sign Up to like & get
recommendations!
Published in 2019 at "Experimental Gerontology"

DOI: 10.1016/j.exger.2018.08.009

Abstract: &NA; Excessive oxidative stress leads to aging due to persistent damage to the cells, tissues, and the entire organism. Immunosenescence is also a devastating consequence of oxidative stress, but there is a lack of research… read more here.

Keywords: induced oxidative; voluntary exercise; immunosenescence; stress ... See more keywords
Photo from wikipedia

Immunosenescence evaluation of peripheral blood lymphocyte subsets in 957 healthy adults from 20 to 95 years old

Sign Up to like & get
recommendations!
Published in 2022 at "Experimental Gerontology"

DOI: 10.1016/j.exger.2021.111615

Abstract: Immunosenescence is characterized by an age-related decline in immune system function. Major efforts have been made to identify changes in peripheral blood lymphocyte subsets accompanying immunosenescence in elderly adults. However, the change trends of some… read more here.

Keywords: blood lymphocyte; age; 957 healthy; immunosenescence ... See more keywords

Altération des réponses vaccinales avec l’âge

Sign Up to like & get
recommendations!
Published in 2019 at "Revue des Maladies Respiratoires"

DOI: 10.1016/j.rmr.2019.07.008

Abstract: Resume Le vieillissement croissant de la population impose de prevenir les infections severes et frequentes sur ce terrain par des vaccins. Cependant, l’immunosenescence altere l’intensite et la qualite des reponses vaccinales, limitant ainsi l'efficacite des… read more here.

Keywords: apres ans; alt ration; reponses vaccinales; des reponses ... See more keywords
Photo by nci from unsplash

Tumor Microenvironment-Regulating Immunosenescence-Independent Nanostimulant Synergizing with Near-Infrared Light Irradiation for Antitumor Immunity.

Sign Up to like & get
recommendations!
Published in 2021 at "ACS applied materials & interfaces"

DOI: 10.1021/acsami.0c20063

Abstract: The combination of photothermal therapy (PTT) and toll-like receptor (TLR)-mediated immunotherapy can elicit antitumor immunity and modulate the immunosuppressive tumor microenvironment (TME). Unlike other TLRs, TLR-5 is a promising target for immune activation, as its… read more here.

Keywords: antitumor immunity; immunosenescence independent; immunosenescence; tlr ... See more keywords
Photo by nci from unsplash

Immunosenescence, inflammaging, and cancer immunotherapy efficacy

Sign Up to like & get
recommendations!
Published in 2022 at "Expert Review of Anticancer Therapy"

DOI: 10.1080/14737140.2022.2098718

Abstract: ABSTRACT Introduction Immunosenescence is a progressive remodeling of immune functions associated with a decreased ability of the immune system to set up an efficient immune response, both innate and adaptive, with an increase of highly… read more here.

Keywords: immunosenescence; immunotherapy; cancer immunotherapy; immunosenescence inflammaging ... See more keywords
Photo by schluditsch from unsplash

An immunologist’s guide to immunosenescence and its treatment

Sign Up to like & get
recommendations!
Published in 2022 at "Expert Review of Clinical Immunology"

DOI: 10.1080/1744666x.2022.2106217

Abstract: ABSTRACT Introduction Aging causes several changes in the immune system, although immune aging is strongly influenced by individual immunological history, as well as genetic and environmental factors leading to inter-individual variability. Areas covered We focused… read more here.

Keywords: immunosenescence; immunologist guide; immunosenescence treatment; guide immunosenescence ... See more keywords
Photo from wikipedia

IMPACT OF OBSTRUCTIVE SLEEP APNOEA AND TREATMENT RESPONSE ON IMMUNOSENESCENCE PARAMETERS IN HYPERTENSION

Sign Up to like & get
recommendations!
Published in 2018 at "Journal of Hypertension"

DOI: 10.1097/01.hjh.0000539239.35803.5f

Abstract: Objective: Inflammation and immunosenescence (IS) have been considered to be associated with hypertension. (HTN) Obstructive sleep apnea (OSA) was also associated with chronic inflammation by repetitive oxidative stress. However, the relationship between immunosenecenece parameters and… read more here.

Keywords: risk; cd8; treatment; value ... See more keywords
Photo by nci from unsplash

Are skin senescence and immunosenescence linked within individuals?

Sign Up to like & get
recommendations!
Published in 2019 at "Aging Cell"

DOI: 10.1111/acel.12956

Abstract: With advancing age, many organs exhibit functional deterioration. The age‐associated accumulation of senescent cells is believed to represent one factor contributing to this phenomenon. While senescent cells are found in several different organ systems, it… read more here.

Keywords: within individuals; senescent cells; senescence; senescence immunosenescence ... See more keywords
Photo by kellysikkema from unsplash

Skin Immunosenescence and Type 2 Inflammation: A Mini-Review With an Inflammaging Perspective

Sign Up to like & get
recommendations!
Published in 2022 at "Frontiers in Cell and Developmental Biology"

DOI: 10.3389/fcell.2022.835675

Abstract: Skin-resident stromal cells, including keratinocytes, fibroblasts, adipocytes, and immune cells including Langerhans cells, dendritic cells, T cells, and innate lymphoid cells, and their functional products work in concert to ensure the realization of skin barrier… read more here.

Keywords: immunosenescence; mini review; type inflammation; immunosenescence type ... See more keywords

Radiation therapy induces immunosenescence mediated by p90RSK

Sign Up to like & get
recommendations!
Published in 2022 at "Frontiers in Cardiovascular Medicine"

DOI: 10.3389/fcvm.2022.988713

Abstract: Radiation therapy (RT) to the chest increases the patients’ risk of cardiovascular disease (CVD). A complete understanding of the mechanisms by which RT induces CVD could lead to specific preventive, therapeutic approaches. It is becoming… read more here.

Keywords: immunosenescence; role; expression; p90rsk ... See more keywords