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Published in 2021 at "Biogerontology"
DOI: 10.1007/s10522-021-09936-9
Abstract: An intricate relationship between impaired immune functions and the age-related accumulation of tissue senescent cells is rapidly emerging. The immune system is unique as it undergoes mutually inclusive and deleterious processes of immunosenescence and cellular…
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Keywords:
senescence;
immunosenescence;
biology;
macrophage ... See more keywords
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Published in 2019 at "Experimental Gerontology"
DOI: 10.1016/j.exger.2018.08.009
Abstract: &NA; Excessive oxidative stress leads to aging due to persistent damage to the cells, tissues, and the entire organism. Immunosenescence is also a devastating consequence of oxidative stress, but there is a lack of research…
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Keywords:
induced oxidative;
voluntary exercise;
immunosenescence;
stress ... See more keywords
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Published in 2022 at "Experimental Gerontology"
DOI: 10.1016/j.exger.2021.111615
Abstract: Immunosenescence is characterized by an age-related decline in immune system function. Major efforts have been made to identify changes in peripheral blood lymphocyte subsets accompanying immunosenescence in elderly adults. However, the change trends of some…
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Keywords:
blood lymphocyte;
age;
957 healthy;
immunosenescence ... See more keywords
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Published in 2019 at "Revue des Maladies Respiratoires"
DOI: 10.1016/j.rmr.2019.07.008
Abstract: Resume Le vieillissement croissant de la population impose de prevenir les infections severes et frequentes sur ce terrain par des vaccins. Cependant, l’immunosenescence altere l’intensite et la qualite des reponses vaccinales, limitant ainsi l'efficacite des…
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Keywords:
apres ans;
alt ration;
reponses vaccinales;
des reponses ... See more keywords
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Published in 2021 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.0c20063
Abstract: The combination of photothermal therapy (PTT) and toll-like receptor (TLR)-mediated immunotherapy can elicit antitumor immunity and modulate the immunosuppressive tumor microenvironment (TME). Unlike other TLRs, TLR-5 is a promising target for immune activation, as its…
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Keywords:
antitumor immunity;
immunosenescence independent;
immunosenescence;
tlr ... See more keywords
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Published in 2022 at "Expert Review of Anticancer Therapy"
DOI: 10.1080/14737140.2022.2098718
Abstract: ABSTRACT Introduction Immunosenescence is a progressive remodeling of immune functions associated with a decreased ability of the immune system to set up an efficient immune response, both innate and adaptive, with an increase of highly…
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Keywords:
immunosenescence;
immunotherapy;
cancer immunotherapy;
immunosenescence inflammaging ... See more keywords
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Published in 2022 at "Expert Review of Clinical Immunology"
DOI: 10.1080/1744666x.2022.2106217
Abstract: ABSTRACT Introduction Aging causes several changes in the immune system, although immune aging is strongly influenced by individual immunological history, as well as genetic and environmental factors leading to inter-individual variability. Areas covered We focused…
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Keywords:
immunosenescence;
immunologist guide;
immunosenescence treatment;
guide immunosenescence ... See more keywords
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Published in 2018 at "Journal of Hypertension"
DOI: 10.1097/01.hjh.0000539239.35803.5f
Abstract: Objective: Inflammation and immunosenescence (IS) have been considered to be associated with hypertension. (HTN) Obstructive sleep apnea (OSA) was also associated with chronic inflammation by repetitive oxidative stress. However, the relationship between immunosenecenece parameters and…
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Keywords:
risk;
cd8;
treatment;
value ... See more keywords
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Published in 2019 at "Aging Cell"
DOI: 10.1111/acel.12956
Abstract: With advancing age, many organs exhibit functional deterioration. The age‐associated accumulation of senescent cells is believed to represent one factor contributing to this phenomenon. While senescent cells are found in several different organ systems, it…
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Keywords:
within individuals;
senescent cells;
senescence;
senescence immunosenescence ... See more keywords
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Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.835675
Abstract: Skin-resident stromal cells, including keratinocytes, fibroblasts, adipocytes, and immune cells including Langerhans cells, dendritic cells, T cells, and innate lymphoid cells, and their functional products work in concert to ensure the realization of skin barrier…
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Keywords:
immunosenescence;
mini review;
type inflammation;
immunosenescence type ... See more keywords
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Published in 2022 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2022.988713
Abstract: Radiation therapy (RT) to the chest increases the patients’ risk of cardiovascular disease (CVD). A complete understanding of the mechanisms by which RT induces CVD could lead to specific preventive, therapeutic approaches. It is becoming…
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Keywords:
immunosenescence;
role;
expression;
p90rsk ... See more keywords