Isolation, purification, structural analysis and immunostimulatory activity of water-soluble polysaccharides from Grifola Frondosa fruiting body.
Sign Up to like & getrecommendations! Published in 2017 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2016.10.082
Abstract: A new polysaccharide had been successfully isolated from maitake mushroom (Grifola Frondosa)-GFP. HPLC and Monosaccharide analysis showed that the average molecular weight of GFP was 155kDa and it was mainly composed of rhamnose, xylose, mannose,… read more here.
Keywords: analysis; immunostimulatory activity; grifola frondosa; gfp ... See more keywords
Structural characterization and immunostimulatory activity in vitro of a glycogen from sea urchin-Strongylocentyotus internedius.
Sign Up to like & getrecommendations! Published in 2021 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2021.117701
Abstract: Sea urchin possesses both high nutritional and medicinal value. It contains diverse biological active polysaccharides. But there are few studies on its glycogen. In the current study, a glucan (MSGA) was separated from Strongylocentyotus internedius… read more here.
Keywords: immunostimulatory activity; strongylocentyotus internedius; sea urchin; activity ... See more keywords
Panax quinquefolius (North American ginseng) cell suspension culture as a source of bioactive polysaccharides: Immunostimulatory activity and characterization of a neutral polysaccharide AGC1.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2019.07.215
Abstract: In this study, we propose the use of a plant tissue culture-based system for the production of polysaccharides with consistent chemical characteristics and reduced endotoxin content. Polysaccharides were isolated from suspension cultures of Panax quinquefolius… read more here.
Keywords: agc1; american ginseng; panax quinquefolius; immunostimulatory activity ... See more keywords
Structural characterization and immunostimulatory activity of a glucan from Cyclina sinensis.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2020.06.020
Abstract: Cyclina sinensis is an edible clam widely distributed along the coastal waters of Asia. In the present study, a polysaccharide (CSP-1) isolated from C. sinensis was purified by a DEAE-Sepharose Fast Flow column, and it… read more here.
Keywords: immunostimulatory activity; sinensis; structural characterization; cyclina sinensis ... See more keywords
Effect of steam explosion pretreatment on polysaccharide isolated from Poria cocos: Structure and immunostimulatory activity.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of food biochemistry"
DOI: 10.1111/jfbc.14355
Abstract: This study aimed to examine the effects of steam explosion (SE) pretreatment on the structural characteristics and immunostimulatory activity of polysaccharide from Poria cocos. Results showed that the average molecular weights of native polysaccharide (PCP)… read more here.
Keywords: pretreatment; structure; steam explosion; pcp ... See more keywords
Characterization and immunostimulatory activity of extracellular vesicles from Filifactor alocis.
Sign Up to like & getrecommendations! Published in 2019 at "Molecular oral microbiology"
DOI: 10.1111/omi.12272
Abstract: Filifactor alocis, a Gram-positive, obligate anaerobic rod, is an emerging periodontal pathogen that is frequently isolated from patients with periodontitis, peri-implantitis, and apical periodontitis. Recent studies have shown that extracellular vesicles (EVs) from Gram-negative periodontal… read more here.
Keywords: extracellular vesicles; immunostimulatory activity; evs; filifactor alocis ... See more keywords
Safety and enhanced immunostimulatory activity of the DRD2 antagonist ONC201 in advanced solid tumor patients with weekly oral administration
Sign Up to like & getrecommendations! Published in 2019 at "Journal for Immunotherapy of Cancer"
DOI: 10.1186/s40425-019-0599-8
Abstract: BackgroundONC201 is a small molecule antagonist of DRD2, a G protein-coupled receptor overexpressed in several malignancies, that has prolonged antitumor efficacy and immunomodulatory properties in preclinical models. The first-in-human trial of ONC201 previously established a… read more here.
Keywords: advanced solid; onc201; enhanced immunostimulatory; solid tumor ... See more keywords
Anticancer and immunostimulatory activity of the imipridone ONC201, a selective DRD2 antagonist, in advanced cancer patients.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.15_suppl.2586
Abstract: 2586Background: ONC201 is an orally active, small molecule selective antagonist of the G protein-coupled receptor DRD2 that has established a new class of compounds referred to as imipridones. A first-in-human trial of ONC201 defined its… read more here.
Keywords: onc201; anticancer immunostimulatory; immunostimulatory activity; drd2 ... See more keywords
Preparation, Structural Features and in vitro Immunostimulatory Activity of a Glucomannan From Fresh Dendrobium catenatum Stems
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Nutrition"
DOI: 10.3389/fnut.2021.823803
Abstract: Dendrobium catenatum polysaccharides (DCPs) have attracted attention due to their multiple physiological activities and health benefits. In this study, a novel water-soluble DCP was obtained from fresh D. catenatum stems through three-phase partitioning and ethanol… read more here.
Keywords: catenatum stems; vitro immunostimulatory; dendrobium catenatum; immunostimulatory activity ... See more keywords
Structural elucidation of a novel arabinogalactan LFP-80-W1 from Lycii fructus with potential immunostimulatory activity
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Nutrition"
DOI: 10.3389/fnut.2022.1067836
Abstract: Polysaccharides are the most important effective components of Lycii fructus, which has a variety of biological activities and broad application prospects in the fields of medicine and food. In this study, we reported a novel… read more here.
Keywords: lycii fructus; lfp; arabinogalactan lfp; novel arabinogalactan ... See more keywords
Immunostimulatory activity of hydrolyzed and fermented Platycodon grandiflorum extract occurs via the MAPK and NF-κB signaling pathway in RAW 264.7 cells
Sign Up to like & getrecommendations! Published in 2022 at "Nutrition Research and Practice"
DOI: 10.4162/nrp.2022.16.6.685
Abstract: BACKGROUND/OBJECTIVES Platycodon grandiflorum (PG) has long been known as a medicinal herb effective in various diseases, including bronchitis and asthma, but is still more widely used for food. Fermentation methods are being applied to increase… read more here.
Keywords: hydrolyzed fermented; 264 cells; platycodon grandiflorum; raw 264 ... See more keywords