The impact of immunosuppressive agents on immune checkpoint inhibitor efficacy in patients with advanced melanoma: A real‐world, multicenter, retrospective study
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DOI: 10.1002/cncr.34742
Abstract: Immune‐related adverse events (irAEs) associated with immune checkpoint inhibitors (ICIs) are often managed via immunosuppressive agents (ISAs); however, their impact on ICI efficacy is not well studied. The impact of the use of ISAs on… read more here.
Keywords: advanced melanoma; immune checkpoint; patients advanced; efficacy patients ... See more keywords
Live attenuated vaccines under immunosuppressive agents or biological agents: survey and clinical data from Japan
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DOI: 10.1007/s00431-021-03927-1
Abstract: Live attenuated vaccines are contraindicated for patients on immunosuppressive agents or biological agent, except for live attenuated varicella vaccine, although previous reports showed their effectiveness and safety. This study is the nationwide cross-sectional research about… read more here.
Keywords: attenuated vaccines; patients receiving; biological agents; live attenuated ... See more keywords
The efficacy and safety of immunosuppressive agents plus steroids compared with steroids alone in the treatment of Henoch–Schönlein purpura nephritis: A meta-analysis
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DOI: 10.1007/s11255-019-02092-7
Abstract: BackgroundHenoch–Schönlein purpura nephritis (HSPN) is the most severe symptom of Henoch–Schönlein purpura. The role of immunosuppressive agents combined with steroids is controversial in treating HSPN. Our meta-analysis was performed to assess the efficacy and safety… read more here.
Keywords: steroids alone; compared steroids; nlein purpura; sch nlein ... See more keywords
COVID-19 in rheumatic disease patients on immunosuppressive agents
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DOI: 10.1016/j.semarthrit.2020.05.010
Abstract: Abstract Objective To analyze clinical characteristics and outcome of COVID-19 patients with underlying rheumatic diseases (RD) on immunosuppressive agents. Method A case series of COVID-19 patients with RD on disease modifying anti-rheumatic drugs (DMARDs) were… read more here.
Keywords: covid rheumatic; rheumatic disease; disease; immunosuppressive agents ... See more keywords
Do immunosuppressive agents hamper the vaccination response in patients with rheumatic diseases? A review of the literature.
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DOI: 10.1016/j.therap.2020.08.002
Abstract: Patients with auto-immune disease are more susceptible to infection than similar populations without auto-immune disease. Vaccination seems to be one of the most effective methods to prevent patients from possible infections, but may be impaired… read more here.
Keywords: vaccination response; agents hamper; vaccination; hamper vaccination ... See more keywords
COVID vaccine recommendations in dermatologic patients on immunosuppressive agents: Lessons learned from pandemic
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DOI: 10.1111/jocd.15448
Abstract: Since SARS‐CoV2 vaccines were approved without enough long‐term monitoring due to emergent situations, some issues have been raised about timing and protocol of receiving them by patients treated by different immunosuppressive agents. read more here.
Keywords: vaccine recommendations; dermatologic patients; recommendations dermatologic; immunosuppressive agents ... See more keywords
Vaccines: Considerations for pediatric dermatology patients on immunosuppressive agents.
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DOI: 10.1111/pde.14631
Abstract: Pediatric dermatologists should be aware of immunization schedules and special recommendations for patients on immunosuppressive agents due to the increased risk of vaccine-preventable infections. Prior to initiating immunosuppressive therapy, pediatric dermatologists should review a vaccine… read more here.
Keywords: considerations pediatric; dermatology; patients immunosuppressive; pediatric dermatology ... See more keywords
Immunogenicity and safety of SARS‐CoV‐2 vaccine with immunosuppressive agents
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DOI: 10.1111/ped.15331
Abstract: Abstract Background We conducted a prospective study of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) messenger RNA (mRNA) vaccination of children and adolescents who were taking immunosuppressive agents. Methods Two doses of SARS‐CoV‐2 mRNA vaccine… read more here.
Keywords: immunogenicity; patients taking; sars cov; taking immunosuppressive ... See more keywords
Abstract 1315: NETs act as immunosuppressive agents within lymph nodes during cancer
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DOI: 10.1158/1538-7445.am2023-1315
Abstract: Metastasis is responsible for 90% of all cancer-related deaths, making it the most significant challenge in cancer treatment for clinicians worldwide. Metastasis is thought to occur in a stepwise process, in which local lymph nodes… read more here.
Keywords: metastasis; cancer; nets act; lymph nodes ... See more keywords
Withanolides as Potential Immunosuppressive Agents against RAW264.7 Cells from the Pericarps of Datura metel
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DOI: 10.1177/1934578x1701200705
Abstract: Two new withanolides, daturafoliside V (1) and daturafoliside W (2) with three known ones, daturametelin J (3), daturataturin A (4) and daturataturin B (5) were isolated from the pericarp of Datura metel L.. The structures… read more here.
Keywords: withanolides potential; datura metel; metel; raw264 cells ... See more keywords
Prospective study of live attenuated vaccines for patients receiving immunosuppressive agents
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DOI: 10.1371/journal.pone.0240217
Abstract: Patients receiving immunosuppressive agents are at risk of life-threatening infections. However, live vaccines are generally contraindicated in them. We conducted a prospective study regarding live attenuated vaccines for them. Patients elder than one year of… read more here.
Keywords: attenuated vaccines; patients receiving; vaccines patients; immunosuppressive agents ... See more keywords