Immunosuppressive effects and associated compensatory responses in zebrafish after full life-cycle exposure to environmentally relevant concentrations of cadmium.
Sign Up to like & getrecommendations! Published in 2017 at "Aquatic toxicology"
DOI: 10.1016/j.aquatox.2017.04.014
Abstract: In natural environments, fish survive in polluted water by cadmium (Cd) throughout their whole life cycle. However, little information is available on Cd toxicity considering a life cycle assessment. The present study investigated effects of… read more here.
Keywords: life cycle; mrna levels; spleen zebrafish; life ... See more keywords
The immunosuppressive effects of a novel recombinant LipQ (Rv2485c) protein of Mycobacterium tuberculosis on human macrophage cell lines.
Sign Up to like & getrecommendations! Published in 2017 at "Microbial pathogenesis"
DOI: 10.1016/j.micpath.2017.04.015
Abstract: Mycobacterium tuberculosis (MTB), an intracellular pathogen, still represents a major global health challenge. A number of mycobacterial macromolecules have been shown to target biological processes within host macrophages; however, the exact mechanism for the majority… read more here.
Keywords: inflammatory cytokines; tuberculosis; macrophage; immunosuppressive effects ... See more keywords
Immunosuppressive Effects of Multiple Myeloma‐Derived Extracellular Vesicles Through T Cell Exhaustion
Sign Up to like & getrecommendations! Published in 2025 at "Cancer Science"
DOI: 10.1111/cas.70099
Abstract: Extracellular vehicles (EVs) are reported to be involved in several processes relating to tumor progression, including angiogenesis, osteolysis, and drug resistance in multiple myeloma (MM). However, the role of EVs in the immune‐suppressive milieu of… read more here.
Keywords: derived evs; multiple myeloma; exhaustion; immunosuppressive effects ... See more keywords
Multiple Immunosuppressive Effects of CpG-c41 on Intracellular TLR-Mediated Inflammation
Sign Up to like & getrecommendations! Published in 2017 at "Mediators of Inflammation"
DOI: 10.1155/2017/6541729
Abstract: A growing body of literature suggests that most chronic autoimmune diseases are associated with inappropriate inflammation mediated by Toll-like receptor (TLR) 3, TLR7/8, or TLR9. Therefore, research into blocking TLR activation to treat these disorders… read more here.
Keywords: effects cpg; inflammation; cpg c41; intracellular tlr ... See more keywords
Reversing Imatinib's Immunosuppressive Effects by Modulating Type I IFN Signaling
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Immunology Research"
DOI: 10.1158/2326-6066.cir-21-0177
Abstract: Signal pathway inhibition is a well-validated approach for treating cancers driven by activated kinases such as KIT. However, kinase inhibitors may make tumor cells less responsive to tumor immune surveillance and less sensitive to immunotherapies.… read more here.
Keywords: imatinib immunosuppressive; type ifn; reversing imatinib; immunosuppressive effects ... See more keywords
Immunosuppressive Effects of Annona muricata L. Leaf Extract on Cellular and Humoral Immune Responses in Male Wistar Rats.
Sign Up to like & getrecommendations! Published in 2022 at "Current pharmaceutical biotechnology"
DOI: 10.2174/1389201024666221221113020
Abstract: BACKGROUND Annona muricata L. (Annonaceae) (AM) 's remarkable anti-inflammatory and anti-cancer activities make it a targeted plant to be explored for its immunomodulatory properties. Traditional practitioners have employed various components of AM to cure a… read more here.
Keywords: leaf extract; immune responses; annona muricata; immunosuppressive effects ... See more keywords
Immunosuppressive effects of vascular endothelial growth factor
Sign Up to like & getrecommendations! Published in 2022 at "Oncology Letters"
DOI: 10.3892/ol.2022.13489
Abstract: Vascular endothelial growth factor (VEGF) serves a critical role in vasculogenesis, angiogenesis, tumor, inflammatory angiogenesis and lymphangiogenesis. Since 2004, bevacizumab (Avastin), a humanized anti-VEGFA monoclonal antibody, has been approved for the treatment of non-small cell… read more here.
Keywords: vegf; endothelial growth; immunosuppressive effects; growth factor ... See more keywords