Human Herpes simplex 1 virus infection of endometrial decidual tissue-derived MSC alters HLA-G expression and immunosuppressive functions.
Sign Up to like & getrecommendations! Published in 2018 at "Human immunology"
DOI: 10.1016/j.humimm.2018.08.006
Abstract: OBJECTIVES Mesenchymal stromal/stem cells have immunosuppressive functions. Our previous results demonstrated that one of the players of this immunomodulation can be ascribed to the Human Leukocyte Antigen-G. HLA-G, a non classical HLA class I antigen,… read more here.
Keywords: edt msc; immunosuppressive functions; infection; hla expression ... See more keywords
Immunosuppressive Functions of M2 Macrophages Derived from iPSCs of Patients with ALS and Healthy Controls
Sign Up to like & getrecommendations! Published in 2020 at "iScience"
DOI: 10.1016/j.isci.2020.101192
Abstract: Summary Amyotrophic lateral sclerosis (ALS) is a disorder with immune alterations that augment disease severity. M2 macrophages benefit diabetic and nephrotic mice by suppressing the pro-inflammatory state. However, neither have M2 cells been investigated in… read more here.
Keywords: functions macrophages; immunosuppressive functions; macrophages derived; ipsc derived ... See more keywords
Induction of immunosuppressive functions and NF-κB by FLIP in monocytes
Sign Up to like & getrecommendations! Published in 2018 at "Nature Communications"
DOI: 10.1038/s41467-018-07654-4
Abstract: Immunosuppression is a hallmark of tumor progression, and treatments that inhibit or deplete monocytic myeloid-derived suppressive cells could promote anti-tumor immunity. c-FLIP is a central regulator of caspase-8-mediated apoptosis and necroptosis. Here we show that… read more here.
Keywords: flip; functions flip; induction immunosuppressive; immunosuppressive functions ... See more keywords
Immunosuppressive functions of melanoma cell-derived exosomes in plasma of melanoma patients
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.1080925
Abstract: Tumor-derived exosomes (TEX) are a subset of small extracellular vesicles (sEV) present in all body fluids of patients with cancer. In plasma of patients with metastatic melanoma, numbers of exosomes produced by melanoma cells called… read more here.
Keywords: derived exosomes; melanoma; melanoma cell; functions melanoma ... See more keywords