Merkel cell carcinoma expresses the immunoregulatory ligand CD200 and induces immunosuppressive macrophages and regulatory T cells
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DOI: 10.1080/2162402x.2018.1426517
Abstract: ABSTRACT Merkel cell carcinoma (MCC) is a rare and aggressive skin cancer that responds to PD-1/PD-L1 immune checkpoint inhibitors. CD200 is another checkpoint modulator whose receptor is found on tumor-promoting myeloid cells, including M2 macrophages.… read more here.
Keywords: mcc; cell carcinoma; regulatory cells; immunosuppressive macrophages ... See more keywords