A Component-Resolved Therapeutic Vaccine for Cockroach Allergy Made of Per a 9 and Transforming Growth Factor-β Homologue, an Immunosuppressive Protein of Brugia malayi
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DOI: 10.3389/fimmu.2021.676558
Abstract: Allergen-specific-immunotherapy (ASIT) can cause long-term resolution of allergic diseases, reduces drug use and chances of new allergen sensitization. Nevertheless, therapeutic vaccine and data on ASIT efficacy for cockroach (CR) allergy are relatively scarce. In this… read more here.
Keywords: protein brugia; therapeutic vaccine; allergy; cockroach allergy ... See more keywords
Immunosuppressive Protein Signatures Carried by Syncytiotrophoblast-Derived Exosomes and Their Role in Human Pregnancy
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DOI: 10.3389/fimmu.2021.717884
Abstract: The syncytiotrophoblast (STB) of human placenta constitutively and throughout pregnancy produces and secretes exosomes - nanometer-sized membrane-bound extracellular vesicles from the endosomal compartment that convey cell-cell contact ‘by proxy’ transporting information between donor and recipient… read more here.
Keywords: pregnancy; derived exosomes; protein signatures; signatures carried ... See more keywords