Carbohydrate Strengthens the Immunotherapeutic Effect of Small-Molecule PD-L1 Inhibitors.
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DOI: 10.1021/acs.jmedchem.2c01347
Abstract: PD-1/PD-L1 checkpoint blockade has demonstrated great success in cancer immunotherapy. Small-molecule PD-L1 inhibitors also attract significant research interests but remain challenging in the efficacy and safety. Carbohydrate moiety and carbohydrate-binding proteins (lectins) play important roles… read more here.
Keywords: molecule inhibitors; small molecule; carbohydrate; effect small ... See more keywords