Articles with "immunotherapeutic strategies" as a keyword



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Emerging immunotherapeutic strategies for the treatment of breast cancer

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Published in 2021 at "Breast Cancer Research and Treatment"

DOI: 10.1007/s10549-021-06406-1

Abstract: Immunotherapy has resulted in unprecedented gains in long-term outcomes for many cancer types and has revolutionized the treatment landscape of solid tumor oncology. Checkpoint inhibition in combination with chemotherapy has proven to be effective for… read more here.

Keywords: immunotherapeutic strategies; treatment; breast cancer; cancer ... See more keywords
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Immunotherapeutic strategies to target vulnerabilities in the Ebolavirus glycoprotein.

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Published in 2021 at "Immunity"

DOI: 10.1016/j.immuni.2021.01.015

Abstract: The 2014 Ebola virus disease (EVD) outbreak in West Africa and the subsequent outbreaks of 2018-2020 in Equator and North Kivu provinces of the Democratic Republic of the Congo illustrate the public health challenges of… read more here.

Keywords: target vulnerabilities; immunotherapeutic strategies; ebolavirus glycoprotein; vulnerabilities ebolavirus ... See more keywords
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PD-L1 regulation revisited: impact on immunotherapeutic strategies.

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Published in 2021 at "Trends in molecular medicine"

DOI: 10.1016/j.molmed.2021.06.005

Abstract: A particularly promising cancer treatment is the use of monoclonal antibodies (mAbs) against immune checkpoints (i.e., immune checkpoint inhibitors; ICIs). However, many patients experience relapse and severe adverse events. To overcome these negative issues and… read more here.

Keywords: impact immunotherapeutic; medicine; immunotherapeutic strategies; revisited impact ... See more keywords
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Immunotherapeutic Strategies for Gastric Carcinoma: A Review of Preclinical and Clinical Recent Development

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Published in 2017 at "BioMed Research International"

DOI: 10.1155/2017/5791262

Abstract: Gastric carcinoma (GC) is the 2nd most common cause of cancer-related death. Despite advances in conventional treatment and surgical interventions, a high percentage of GC patients still have poor survival. Recently, immunotherapy has become a… read more here.

Keywords: gastric carcinoma; immunotherapeutic strategies; strategies gastric; carcinoma review ... See more keywords
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Implications of IDH mutations on immunotherapeutic strategies for malignant glioma.

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Published in 2022 at "Neurosurgical focus"

DOI: 10.3171/2021.11.focus21604

Abstract: Immunotherapy has emerged as a promising approach for treating aggressive solid tumors, even within the CNS. Mutation in the metabolic gene isocitrate dehydrogenase 1 (IDH1) represents not only a major glioma defining biomarker but also… read more here.

Keywords: implications idh; mutations immunotherapeutic; malignant glioma; idh mutations ... See more keywords
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Immunotherapeutic Strategies in Cancer and Atherosclerosis—Two Sides of the Same Coin

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Published in 2022 at "Frontiers in Cardiovascular Medicine"

DOI: 10.3389/fcvm.2021.812702

Abstract: The development and clinical approval of immunotherapies has revolutionized cancer therapy. Although the role of adaptive immunity in atherogenesis is now well-established and several immunomodulatory strategies have proven beneficial in preclinical studies, anti-atherosclerotic immunotherapies available… read more here.

Keywords: cancer atherosclerosis; strategies cancer; immune responses; immunotherapeutic strategies ... See more keywords
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Humanized Mouse Models for the Study of Periodontitis: An Opportunity to Elucidate Unresolved Aspects of Its Immunopathogenesis and Analyze New Immunotherapeutic Strategies

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Published in 2021 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2021.663328

Abstract: Periodontitis is an oral inflammatory disease in which the polymicrobial synergy and dysbiosis of the subgingival microbiota trigger a deregulated host immune response, that leads to the breakdown of tooth-supporting tissues and finally tooth loss.… read more here.

Keywords: mouse models; immunotherapeutic strategies; response; immune response ... See more keywords
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In Vitro Diffuse Large B-Cell Lymphoma Cell Line Models as Tools to Investigate Novel Immunotherapeutic Strategies

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Published in 2022 at "Cancers"

DOI: 10.3390/cancers15010235

Abstract: Simple Summary Despite a range of emerging immunotherapeutic strategies, the aggressive nature of DLBCL poses an ongoing clinical challenge. Therefore, there is a need to pursue more effective treatment modalities based on monoclonal antibodies, antibody-drug… read more here.

Keywords: cell; cell line; dlbcl; line ... See more keywords