Association of Immunotherapy With Survival Among Patients With Brain Metastases Whose Cancer Was Managed With Definitive Surgery of the Primary Tumor
Sign Up to like & getrecommendations! Published in 2020 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2020.15444
Abstract: Key Points Question Is combining immunotherapy with other cancer treatments associated with improved overall survival in patients with brain metastases? Findings In this comparative effectiveness study of 3112 adult patients who received definitive surgery of… read more here.
Keywords: improved overall; immunotherapy; associated improved; cancer ... See more keywords
Racial and Ethnic Representation in Food Allergen Immunotherapy Trial Participants
Sign Up to like & getrecommendations! Published in 2024 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2024.32710
Abstract: Key Points Question What are the racial and ethnic distributions observed among participants in food allergy immunotherapy trials? Findings In this systematic review of 26 randomized clinical trials, the predominant racial demographic group represented within… read more here.
Keywords: food allergy; food; immunotherapy; trial ... See more keywords
Association of Patient Sex With Efficacy of Immune Checkpoint Inhibitors and Overall Survival in Advanced Cancers: A Systematic Review and Meta-analysis
Sign Up to like & getrecommendations! Published in 2019 at "JAMA Oncology"
DOI: 10.1001/jamaoncol.2018.5904
Abstract: Importance Sex-associated differences in immune response are known, but a meta-analysis suggested men, compared with women, derive greater value from immunotherapy for advanced solid-organ malignant neoplasms. However, methodologic concerns and subsequent trials have placed these… read more here.
Keywords: immunotherapy; patient sex; sex; overall survival ... See more keywords
Adoption of Innovative Therapies Across Oncology Practices-Evidence From Immunotherapy.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA oncology"
DOI: 10.1001/jamaoncol.2022.6296
Abstract: Importance Immunotherapies reflect an important breakthrough in cancer treatment, substantially improving outcomes for patients with a variety of cancer types, yet little is known about which practices have adopted this novel therapy or the pace… read more here.
Keywords: oncology; practice; immunotherapy; adoption ... See more keywords
NIR/ROS‐Responsive Black Phosphorus QD Vesicles as Immunoadjuvant Carrier for Specific Cancer Photodynamic Immunotherapy
Sign Up to like & getrecommendations! Published in 2019 at "Advanced Functional Materials"
DOI: 10.1002/adfm.201905758
Abstract: 2D black phosphorus (BP) nanosheets and BP quantum dots (BPQD), as two main material styles of BP, are widely used in the biomedical filed. However, few stimuli‐responsive BP nanocarriers are reported to meet the need… read more here.
Keywords: bpnvs; nir ros; photodynamic immunotherapy; immunotherapy ... See more keywords
Enhancing Triple Negative Breast Cancer Immunotherapy by ICG‐Templated Self‐Assembly of Paclitaxel Nanoparticles
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DOI: 10.1002/adfm.201906605
Abstract: Combination cancer immunotherapy has shown promising potential for simultaneously eliciting antitumor immunity and modulating the immunosuppressive tumor microenvironment (ITM). However, combination immunotherapy with multiple regimens suffers from the varied chemo‐physical properties and inconsistent pharmacokinetic profiles… read more here.
Keywords: tumor; templated self; self assembly; icg templated ... See more keywords
Harnessing DNA for Immunotherapy: Cancer, Infectious Diseases, and Beyond
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DOI: 10.1002/adfm.202112273
Abstract: Despite the rapid development of immunotherapy, low response rates, poor therapeutic outcomes, and severe side effects still limit its implementation, making the augmentation of immunotherapy an important goal for current research. DNA, which is principally… read more here.
Keywords: harnessing dna; immunotherapy cancer; cancer infectious; dna ... See more keywords
Self‐Carrier Nanoparticles for Delivery of Paclitaxel and IDO Inhibitor to Boost Antitumor Chemo‐Immunotherapy
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DOI: 10.1002/adfm.202312500
Abstract: The combination of chemotherapy and immunotherapy holds great potential in clinical treatment of advanced cancers. Whereas, the therapeutic outcome of chemotherapeutic and immune regulator is suboptimal due to their poor tumor availability and severe off‐target… read more here.
Keywords: chemo immunotherapy; self carrier; carrier nanoparticles; immunotherapy ... See more keywords
A Smart Responsive Nanotheranostic System for MRI of Tumor Response to Immunotherapy and Enhanced Synergism of Thermo‐Immunotherapy
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DOI: 10.1002/adfm.202315171
Abstract: The challenges associated with the assessment of immune checkpoint inhibitor (ICI) therapy and low immunotherapy response observed in patients with poorly immunogenic tumors are addressed. A smart‐responsive nanoprobe MZF@Gd is synthetized based on magnetic resonance… read more here.
Keywords: immunotherapy; response; mzf; tumor ... See more keywords
Unleashing a Dual‐Warhead Nanomedicine to Precisely Sensitize Immunotherapy for Pancreatic Ductal Adenocarcinoma
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DOI: 10.1002/adfm.202315447
Abstract: Despite remarkable achievements in cancer immunotherapy, significant challenges persist in pancreatic ductal adenocarcinoma (PDAC) treatment. Particularly, there is a critical issue of inadequate intratumoral infiltration of effector T cells, primarily attributed to the physical “hard”… read more here.
Keywords: dual warhead; ductal adenocarcinoma; warhead nanomedicine; immunotherapy ... See more keywords
MOF‐Coated Upconversion Nanoparticle Agents Enable Synergistic Photodynamic Therapy and Immunotherapy
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DOI: 10.1002/adfm.202401272
Abstract: Although conventional therapeutic approaches demonstrate significant success in treating primary tumors, their efficacy diminishes when addressing distant and metastatic tumors, calling for new technologies to transport and activate the therapeutic agents. Here, a core‐shell UCNP@MOF… read more here.
Keywords: mof; immunotherapy; upconversion nanoparticle; photodynamic therapy ... See more keywords