Association of Immunotherapy With Survival Among Patients With Brain Metastases Whose Cancer Was Managed With Definitive Surgery of the Primary Tumor
Sign Up to like & getrecommendations! Published in 2020 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2020.15444
Abstract: Key Points Question Is combining immunotherapy with other cancer treatments associated with improved overall survival in patients with brain metastases? Findings In this comparative effectiveness study of 3112 adult patients who received definitive surgery of… read more here.
Keywords: improved overall; immunotherapy; associated improved; cancer ... See more keywords
Association of Patient Sex With Efficacy of Immune Checkpoint Inhibitors and Overall Survival in Advanced Cancers: A Systematic Review and Meta-analysis
Sign Up to like & getrecommendations! Published in 2019 at "JAMA Oncology"
DOI: 10.1001/jamaoncol.2018.5904
Abstract: Importance Sex-associated differences in immune response are known, but a meta-analysis suggested men, compared with women, derive greater value from immunotherapy for advanced solid-organ malignant neoplasms. However, methodologic concerns and subsequent trials have placed these… read more here.
Keywords: immunotherapy; patient sex; sex; overall survival ... See more keywords
Adoption of Innovative Therapies Across Oncology Practices-Evidence From Immunotherapy.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA oncology"
DOI: 10.1001/jamaoncol.2022.6296
Abstract: Importance Immunotherapies reflect an important breakthrough in cancer treatment, substantially improving outcomes for patients with a variety of cancer types, yet little is known about which practices have adopted this novel therapy or the pace… read more here.
Keywords: oncology; practice; immunotherapy; adoption ... See more keywords
NIR/ROS‐Responsive Black Phosphorus QD Vesicles as Immunoadjuvant Carrier for Specific Cancer Photodynamic Immunotherapy
Sign Up to like & getrecommendations! Published in 2019 at "Advanced Functional Materials"
DOI: 10.1002/adfm.201905758
Abstract: 2D black phosphorus (BP) nanosheets and BP quantum dots (BPQD), as two main material styles of BP, are widely used in the biomedical filed. However, few stimuli‐responsive BP nanocarriers are reported to meet the need… read more here.
Keywords: bpnvs; nir ros; photodynamic immunotherapy; immunotherapy ... See more keywords
Enhancing Triple Negative Breast Cancer Immunotherapy by ICG‐Templated Self‐Assembly of Paclitaxel Nanoparticles
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DOI: 10.1002/adfm.201906605
Abstract: Combination cancer immunotherapy has shown promising potential for simultaneously eliciting antitumor immunity and modulating the immunosuppressive tumor microenvironment (ITM). However, combination immunotherapy with multiple regimens suffers from the varied chemo‐physical properties and inconsistent pharmacokinetic profiles… read more here.
Keywords: tumor; templated self; self assembly; icg templated ... See more keywords
Harnessing DNA for Immunotherapy: Cancer, Infectious Diseases, and Beyond
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DOI: 10.1002/adfm.202112273
Abstract: Despite the rapid development of immunotherapy, low response rates, poor therapeutic outcomes, and severe side effects still limit its implementation, making the augmentation of immunotherapy an important goal for current research. DNA, which is principally… read more here.
Keywords: harnessing dna; immunotherapy cancer; cancer infectious; dna ... See more keywords
A Freeze‐Concentration and Polyampholyte‐Modified Liposome‐Based Antigen‐Delivery System for Effective Immunotherapy
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DOI: 10.1002/adhm.201700207
Abstract: &NA; Immunotherapy is an exciting new approach to cancer treatment. The development of a novel freeze‐concentration method is described that could be applicable in immunotherapy. The method involves freezing cells in the presence of pH‐sensitive,… read more here.
Keywords: freeze concentration; polyampholyte modified; immunotherapy; delivery ... See more keywords
Recent Progress in the Synergistic Combination of Nanoparticle-Mediated Hyperthermia and Immunotherapy for Treatment of Cancer.
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DOI: 10.1002/adhm.202001415
Abstract: Immunotherapy has demonstrated great clinical success in certain cancers, driven primarily by immune checkpoint blockade and adoptive cell therapies. Immunotherapy can elicit strong, durable responses in some patients, but others do not respond, and to… read more here.
Keywords: combination; progress; immunotherapy; nanoparticle ... See more keywords
Soft X-Ray Stimulated Lanthanide@MOF Nanoprobe for Amplifying Deep Tissue Synergistic Photodynamic and Antitumor Immunotherapy.
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DOI: 10.1002/adhm.202101174
Abstract: Combining photodynamic therapy (PDT) and immunotherapy has shown profound impact for synergistic treatment of malignant tumors. However, the shallow penetration depth of the traditional visible light activated PDT, immunosuppressive tumor microenvironment (TME), and poor immunogenicity… read more here.
Keywords: deep tissue; immunotherapy; ray; pdt ... See more keywords
Synthetic and Biodegradable Molybdenum(IV) Diselenide Triggers the Cascade Photo‐ and Immunotherapy of Tumor
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DOI: 10.1002/adhm.202200524
Abstract: In this study, a polyvinylpyrrolidone (PVP)‐decorated MoSe2 (MoSe2‐PVP) nanoparticle with excellent photothermal transforming ability and chlorin E6 (Ce6) loading capacity is designed for combined tumor photothermal therapy (PTT), tumor photodynamic therapy (PDT), and immunotherapy. The… read more here.
Keywords: synthetic biodegradable; biodegradable molybdenum; immunotherapy; pvp ... See more keywords
Functional 2D Iron‐Based Nanosheets for Synergistic Immunotherapy, Phototherapy, and Chemotherapy of Tumor
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DOI: 10.1002/adhm.202200776
Abstract: Immunotherapy efficacy has been limited by tumor‐associated macrophages (TAMs), which are the most abundant immune regulatory cells infiltrating around tumor tissues. The repolarization of pro‐tumor M2 TAMs to anti‐tumor M1 TAMs is a very promising… read more here.
Keywords: based nanosheets; immunotherapy; repolarize tams; tumor ... See more keywords