Anti‐Cytokine Active Immunotherapy Based on Supramolecular Peptides for Alleviating IL‐1β‐Mediated Inflammation
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202401444
Abstract: IL‐1β is a principal proinflammatory cytokine underlying multiple local and systemic chronic inflammatory conditions including psoriasis, rheumatoid arthritis, inflammatory bowel disease, and type 2 diabetes. Passive immunotherapies and biologic drugs targeting IL‐1β, while offering significant… read more here.
Keywords: cytokine active; immunotherapy; immunotherapy based; anti cytokine ... See more keywords
Development of cancer immunotherapy based on PD-1/PD-L1 pathway blockade
Sign Up to like & getrecommendations! Published in 2019 at "RSC Advances"
DOI: 10.1039/c9ra04590b
Abstract: The possible reasons that caused low response rate and severe side effects of programmed death receptor 1 (PD-1)/programmed death ligand 1 (PD-L1) blockade therapy and corresponding strategies. read more here.
Keywords: pathway blockade; immunotherapy based; development cancer; cancer immunotherapy ... See more keywords
Recent advances in immunotherapy-involved combination cancer therapy based on ZIF-8
Sign Up to like & getrecommendations! Published in 2024 at "AIP Advances"
DOI: 10.1063/5.0232660
Abstract: This paper introduces and briefly describes the tumor immune cycle to clarify the action mechanisms and principles of classical immunotherapy. We then focus on the classification of immunotherapies. Immunotherapy strategies can be classified into three… read more here.
Keywords: therapy; combination; immunotherapy; advances immunotherapy ... See more keywords
Immunotherapy based approaches in myelofibrosis
Sign Up to like & getrecommendations! Published in 2017 at "Expert Review of Hematology"
DOI: 10.1080/17474086.2017.1366853
Abstract: ABSTRACT Introduction: Aberrant regulation of the immune system with up-regulation of pro-inflammatory cytokines contributes to disease pathophysiology in myelofibrosis (MF). Therapeutic options for MF associated anemia, thrombocytopenia, and bone marrow fibrosis remain limited. Areas covered:… read more here.
Keywords: hematology; myelofibrosis; based approaches; approaches myelofibrosis ... See more keywords
Predictors of survival in immunotherapy‐based treatments in advanced melanoma: a meta‐analysis
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Dermatology"
DOI: 10.1111/ijd.17379
Abstract: The introduction of immunotherapy‐based strategies has significantly improved the prognosis for melanoma patients. Nevertheless, some patients still have dismal outcomes, emphasizing the significance of survival predictive indicators in immunotherapy‐based approaches. We systematically searched randomized controlled… read more here.
Keywords: based treatments; immunotherapy; analysis; melanoma patients ... See more keywords
Bispecific immunotherapy based on antibodies, T-cell receptors, and aptamers: mechanisms of action, adverse effects, and future perspectives
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2025.1679092
Abstract: Over the past decade, bispecific immunotherapeutic platforms have progressed from laboratory prototypes to multicenter clinical trials, inaugurating a new trajectory for precision oncology. This review synthesizes original studies that address the design principles, mechanisms of… read more here.
Keywords: immunotherapy based; mechanisms action; based antibodies; bispecific immunotherapy ... See more keywords
CT-based radiomics in predicting pathological response in non-small cell lung cancer patients receiving neoadjuvant immunotherapy
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.937277
Abstract: Objectives In radiomics, high-throughput algorithms extract objective quantitative features from medical images. In this study, we evaluated CT-based radiomics features, clinical features, in-depth learning features, and a combination of features for predicting a good pathological… read more here.
Keywords: immunotherapy based; radiomics features; patients receiving; model ... See more keywords
Current Approaches in Surgical and Immunotherapy-Based Management of Renal Cell Carcinoma with Tumor Thrombus
Sign Up to like & getrecommendations! Published in 2023 at "Biomedicines"
DOI: 10.3390/biomedicines11010204
Abstract: Renal cell carcinoma (RCC) accounts for 2–3% of all malignant disease in adults, with 30% of RCC diagnosed at locally advanced or metastatic stages of disease. A form of locally advanced disease is the tumor… read more here.
Keywords: cell carcinoma; renal cell; immunotherapy based; tumor ... See more keywords
New Challenges Facing Systemic Therapies of Advanced HCC in the Era of Different First-Line Immunotherapy-Based Combinations
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14235868
Abstract: Simple Summary In this review, we detail the data on a new treatment of hepatocellular carcinoma. A new combination of therapies, based on immunotherapy, has recently emerged as efficacious treatment. While being very interesting for… read more here.
Keywords: immunotherapy based; first line; line; based combinations ... See more keywords
Comparison of clinical outcomes in patients with advanced pulmonary sarcomatoid carcinoma treated with immunotherapy-based regimens or chemotherapy: A study based on the SEER database and multicentric real-world settings.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of cancer research and therapeutics"
DOI: 10.4103/jcrt.jcrt_479_24
Abstract: BACKGROUND Pulmonary sarcomatoid carcinoma (PSC) is a rare lung cancer characterized by early metastasis and invasion. It is predominantly diagnosed at a locally advanced or metastatic stage, hindering the possibility of surgical intervention. However, a… read more here.
Keywords: immunotherapy; based regimens; patients advanced; immunotherapy based ... See more keywords
Nanocarriers for pancreatic cancer imaging, treatments, and immunotherapies
Sign Up to like & getrecommendations! Published in 2022 at "Theranostics"
DOI: 10.7150/thno.64805
Abstract: Pancreatic tumors are highly desmoplastic and immunosuppressive. Delivery and distribution of drugs within pancreatic tumors are compromised due to intrinsic physical and biochemical stresses that lead to increased interstitial fluid pressure, vascular compression, and hypoxia.… read more here.
Keywords: pancreatic cancer; immunotherapy based; based approaches; pancreatic tumors ... See more keywords