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Published in 2019 at "RSC Advances"
DOI: 10.1039/c9ra04590b
Abstract: The possible reasons that caused low response rate and severe side effects of programmed death receptor 1 (PD-1)/programmed death ligand 1 (PD-L1) blockade therapy and corresponding strategies.
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Keywords:
pathway blockade;
immunotherapy based;
development cancer;
cancer immunotherapy ... See more keywords
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Published in 2017 at "Expert Review of Hematology"
DOI: 10.1080/17474086.2017.1366853
Abstract: ABSTRACT Introduction: Aberrant regulation of the immune system with up-regulation of pro-inflammatory cytokines contributes to disease pathophysiology in myelofibrosis (MF). Therapeutic options for MF associated anemia, thrombocytopenia, and bone marrow fibrosis remain limited. Areas covered:…
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Keywords:
hematology;
myelofibrosis;
based approaches;
approaches myelofibrosis ... See more keywords
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Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.937277
Abstract: Objectives In radiomics, high-throughput algorithms extract objective quantitative features from medical images. In this study, we evaluated CT-based radiomics features, clinical features, in-depth learning features, and a combination of features for predicting a good pathological…
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Keywords:
immunotherapy based;
radiomics features;
patients receiving;
model ... See more keywords
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Published in 2023 at "Biomedicines"
DOI: 10.3390/biomedicines11010204
Abstract: Renal cell carcinoma (RCC) accounts for 2–3% of all malignant disease in adults, with 30% of RCC diagnosed at locally advanced or metastatic stages of disease. A form of locally advanced disease is the tumor…
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Keywords:
cell carcinoma;
renal cell;
immunotherapy based;
tumor ... See more keywords
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Published in 2022 at "Cancers"
DOI: 10.3390/cancers14235868
Abstract: Simple Summary In this review, we detail the data on a new treatment of hepatocellular carcinoma. A new combination of therapies, based on immunotherapy, has recently emerged as efficacious treatment. While being very interesting for…
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Keywords:
immunotherapy based;
first line;
line;
based combinations ... See more keywords
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Published in 2022 at "Theranostics"
DOI: 10.7150/thno.64805
Abstract: Pancreatic tumors are highly desmoplastic and immunosuppressive. Delivery and distribution of drugs within pancreatic tumors are compromised due to intrinsic physical and biochemical stresses that lead to increased interstitial fluid pressure, vascular compression, and hypoxia.…
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Keywords:
pancreatic cancer;
immunotherapy based;
based approaches;
pancreatic tumors ... See more keywords