Improving immunotherapy outcomes with anti-angiogenic treatments and vice versa
Sign Up to like & getrecommendations! Published in 2018 at "Nature Reviews Clinical Oncology"
DOI: 10.1038/nrclinonc.2018.9
Abstract: Immunotherapies have revolutionized medical oncology following the remarkable and, in some cases, unprecedented outcomes observed in certain groups of patients with cancer. Combination with other therapeutic modalities, including anti-angiogenic agents, is one of the many… read more here.
Keywords: angiogenic treatments; improving immunotherapy; outcomes anti; immunotherapy outcomes ... See more keywords
Diet Influences Immunotherapy Outcomes in Cancer Patients: A Literature Review
Sign Up to like & getrecommendations! Published in 2022 at "Nutrition and Cancer"
DOI: 10.1080/01635581.2022.2133151
Abstract: Abstract The outbreak of immunotherapy has revolutionized cancer treatment. Despite the results confirming the effectiveness of immunotherapy, some studies have reported poor responsiveness to this therapeutic approach. The effectiveness of immunotherapy is dependent on numerous… read more here.
Keywords: diet influences; cancer patients; immunotherapy outcomes; outcomes cancer ... See more keywords
Association of PD-1/PD-L1 Co-location with Immunotherapy Outcomes in Non–Small Cell Lung Cancer
Sign Up to like & getrecommendations! Published in 2021 at "Clinical Cancer Research"
DOI: 10.1158/1078-0432.ccr-21-2649
Abstract: Purpose: Programmed cell death protein 1 (PD-1)/programmed death-ligand 1 (PD-L1) interaction suppresses local T-cell responses and promotes peripheral tolerance. In the current study, we focus on PD-1/PD-L1 co-location as a surrogate for this interaction and… read more here.
Keywords: immunotherapy; cancer; location; immunotherapy outcomes ... See more keywords
Abstract 7380: Predicting immunotherapy outcomes from H&E images in lung cancer
Sign Up to like & getrecommendations! Published in 2024 at "Cancer Research"
DOI: 10.1158/1538-7445.am2024-7380
Abstract: Checkpoint blockade immunotherapy is a cornerstone of lung cancer treatment, but there is a need to improve the identification of patients who will respond favorably. Here, we explored a deep learning approach to predict immunotherapy… read more here.
Keywords: cancer; lung cancer; pathology; immunotherapy outcomes ... See more keywords
Abstract 179: Spatial and multiomics analysis reveals immune interactions as key drivers of immunotherapy outcomes in melanoma patients with in-transit metastases
Sign Up to like & getrecommendations! Published in 2025 at "Cancer Research"
DOI: 10.1158/1538-7445.am2025-179
Abstract: In-transit metastasis (ITM) of melanoma occurs between the primary tumor and draining lymph nodes. ITM can be managed by by adjuvant immunotherapy after resection, or immunotherapy alone when unresectable. Nevertheless, nearly half of ITM patients… read more here.
Keywords: pre responders; immune interactions; analysis; tumor ... See more keywords
Clinicopathologic characteristics and immunotherapy outcomes in SMARCA4-mutant (mut) non-small cell lung cancer (NSCLC).
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.9577
Abstract: 9577Background: The catalytic unit of the SWI/SNF chromatin remodeling complex is encoded by the SMARCA4 gene, which is mutated in ~10% of NSCLCs. We sought to characterize the clinicopathologic ch... read more here.
Keywords: immunotherapy outcomes; smarca4 mutant; mutant mut; clinicopathologic characteristics ... See more keywords
The role of microbiota in immunotherapy outcomes in colorectal cancer patients: A protocol for a systematic review
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0273314
Abstract: In the human gut, there are many microbes, including bacteria, viruses and parasites. The imbalance in the numbers of each type of these microbes can translate into gastrointestinal disorders. Lately, different microbiota patterns have been… read more here.
Keywords: immunotherapy; colorectal cancer; immunotherapy outcomes; systematic review ... See more keywords
Pyroptosis predicts immunotherapy outcomes across multiple cancer types.
Sign Up to like & getrecommendations! Published in 2022 at "Clinical immunology"
DOI: 10.2139/ssrn.4065598
Abstract: Pyroptosis is a programmed cell death characterized by inflammation and may coordinate with cancer immunotherapy, but assessments of pyroptosis in patients with immunotherapy are lacking. We evaluated the pyroptosis potentials in 71 cohorts with 24,388… read more here.
Keywords: pyroptosis potentials; pyroptosis; immunotherapy outcomes; pyroptosis predicts ... See more keywords
Associations of HER2 Mutation With Immune-Related Features and Immunotherapy Outcomes in Solid Tumors
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.799988
Abstract: Background HER2 is one of the most extensively studied oncogenes in solid tumors. However, the association between tumor microenvironment (TME) and HER2 mutation remains elusive, and there are no specific therapies for HER2-mutated tumors. Immune… read more here.
Keywords: immunotherapy outcomes; her2 mutations; solid tumors; mutation ... See more keywords