Cuproptosis-Mediated Patterns Characterized by Distinct Tumor Microenvironment and Predicted the Immunotherapy Response for Gastric Cancer
Sign Up to like & getrecommendations! Published in 2023 at "ACS Omega"
DOI: 10.1021/acsomega.2c07052
Abstract: Cuproptosis is a newly discovered programmed cell death process, and several cuproptosis-related genes have been reported to regulate cancer cell proliferation and progression. The association between cuproptosis and tumor microenvironment in gastric cancer (GC) remains… read more here.
Keywords: immunotherapy response; cuproptosis; cancer; tumor microenvironment ... See more keywords
Construction of immune-related LncRNAs classifier to predict prognosis and immunotherapy response in thymic epithelial tumors
Sign Up to like & getrecommendations! Published in 2022 at "Bioscience Reports"
DOI: 10.1042/bsr20220317
Abstract: Abstract The primary objective of this study was to construct an immune-related long noncoding RNAs (IRLs) classifier to precisely predict the prognosis and immunotherapy response of patients with thymic epithelial tumors (TET). Based on univariable… read more here.
Keywords: immunotherapy; predict prognosis; immunotherapy response; irl classifier ... See more keywords
Role of radiomics in predicting immunotherapy response
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Imaging and Radiation Oncology"
DOI: 10.1111/1754-9485.13426
Abstract: Immunotherapies have revolutionised cancer management. Despite their success, durable responses are limited to a subset of patients. Prediction of immunotherapy response in patients has proven to be difficult due to a lack of robust biomarkers.… read more here.
Keywords: role radiomics; predicting immunotherapy; immunotherapy response; radiomics predicting ... See more keywords
Baseline prognostic nutritional index and changes in pretreatment body mass index associate with immunotherapy response in patients with advanced cancer
Sign Up to like & getrecommendations! Published in 2020 at "Journal for Immunotherapy of Cancer"
DOI: 10.1136/jitc-2020-001674
Abstract: Background Recent research suggests that baseline body mass index (BMI) is associated with response to immunotherapy. In this study, we test the hypothesis that worsening nutritional status prior to the start of immunotherapy, rather than… read more here.
Keywords: index; response; immunotherapy response; baseline ... See more keywords
Identification and Validation of a Novel Multiomics Signature for Prognosis and Immunotherapy Response of Endometrial Carcinoma
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DOI: 10.1155/2022/8998493
Abstract: Purpose Cancer development and immune escape involve DNA methylation, copy number variation, and other molecular events. However, there are remarkably few studies integrating multiomics genetic profiles into endometrial cancer (EC). This study aimed to develop… read more here.
Keywords: immunotherapy response; multiomics signature; signature; validation ... See more keywords
Abstract B24: Digital signatures of T cell dysfunction predict immunotherapy response
Sign Up to like & getrecommendations! Published in 2018 at "Cancer immunology research"
DOI: 10.1158/2326-6074.tumimm17-b24
Abstract: Despite success in treating several cancer types, immunotherapy only shows response in a subset of patients. Predicting immunotherapy response and understanding the resistance mechanisms are still open questions. We present a computational framework, Tumor Immune… read more here.
Keywords: cell dysfunction; immunotherapy response; response; immunology ... See more keywords
Immunotherapy response evaluation with magnetic resonance elastography (MRE) in advanced HCC
Sign Up to like & getrecommendations! Published in 2019 at "Journal for Immunotherapy of Cancer"
DOI: 10.1186/s40425-019-0766-y
Abstract: BackgroundCurrently, there are no imaging predictors of immunotherapy outcome in hepatocellular carcinoma (HCC). The study aim was to determine if stiffness changes measured by magnetic resonance elastography (MRE) can be a predictor of immunotherapy response… read more here.
Keywords: mre; stiffness; hcc stiffness; immunotherapy response ... See more keywords
Immunotherapy response evaluation with MR elastography (MRE) in advanced HCC.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2019.37.4_suppl.230
Abstract: 230 Background: To determine changes in MRE HCC stiffness as predictor of immunotherapy response in patients with advanced HCC. Methods: This was a prospective, Institutional Review Board approved study of 15 patients with biopsy proven… read more here.
Keywords: hcc stiffness; hcc; advanced hcc; stiffness ... See more keywords
Liquid biopsy using plasma proteomic profiling to reveal predictors of immunotherapy response.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2019.37.8_suppl.130
Abstract: 130 Background: The response of metastatic melanoma to anti-PD1 is heterogeneous. We performed proteomic profiling of patient plasma samples to build a predictor of immunotherapy response and uncover biological insights underlying primary resistance. Methods: 58… read more here.
Keywords: response; proteomic profiling; treatment; anti pd1 ... See more keywords
COL12A1 as a prognostic biomarker links immunotherapy response in breast cancer.
Sign Up to like & getrecommendations! Published in 2023 at "Endocrine-related cancer"
DOI: 10.1530/erc-23-0012
Abstract: Immunotherapy has shown promising efficacy for breast cancer (BC) patients. Yet the predictive biomarkers for immunotherapy response remains lacking. Based on two GEO datasets, 53 differentially expressed genes (DEGs) associated with durvalumab treatment response, were… read more here.
Keywords: breast cancer; response; col12a1; immunotherapy response ... See more keywords
Predicting cancer immunotherapy response from gut microbiomes using machine learning models
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DOI: 10.18632/oncotarget.28252
Abstract: Cancer immunotherapy has significantly improved patient survival. Yet, half of patients do not respond to immunotherapy. Gut microbiomes have been linked to clinical responsiveness of melanoma patients on immunotherapies; however, different taxa have been associated… read more here.
Keywords: response; gut; immunotherapy response; cancer immunotherapy ... See more keywords