Emerging immunotherapy targets in lung cancer
Sign Up to like & getrecommendations! Published in 2020 at "Chinese Medical Journal"
DOI: 10.1097/cm9.0000000000001082
Abstract: Abstract Immunotherapy has become the mainstay for lung cancer treatment, providing sustained therapeutic responses and improved prognosis compared with those obtained with surgery, chemotherapy, radiotherapy, and targeted therapy. It has the potential for anti-tumor treatment… read more here.
Keywords: emerging immunotherapy; targets lung; lung cancer; cancer ... See more keywords
Expanding the landscape of immunotherapy targets
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DOI: 10.1126/science.362.6419.1124-t
Abstract: Cancer Most searches for druggable tumor-specific antigens (TSAs) start with an examination of peptides derived from protein-coding exons. Laumont et al. took a different approach and found numerous TSAs that derived from aberrant expression of… read more here.
Keywords: expanding landscape; cancer; landscape immunotherapy; immunotherapy targets ... See more keywords
Computational Discovery of Cancer Immunotherapy Targets by Intercellular CRISPR Screens
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.884561
Abstract: Cancer immunotherapy targets the interplay between immune and cancer cells. In particular, interactions between cytotoxic T lymphocytes (CTLs) and cancer cells, such as PD-1 (PDCD1) binding PD-L1 (CD274), are crucial for cancer cell clearance. However,… read more here.
Keywords: cell; crispr screens; intercellular crispr; immunotherapy targets ... See more keywords