Intraventricular immunovirotherapy; a translational step forward
Sign Up to like & getrecommendations! Published in 2023 at "Oncotarget"
DOI: 10.18632/oncotarget.28343
Abstract: Oncolytic virotherapy with intratumoral engineered type-1 herpes simplex virus (HSV) has been proven safe with promising efficacy in recent clinical trials for treatment of both pediatric and adult high-grade glioma. However, this approach excludes patients… read more here.
Keywords: translational step; step forward; intraventricular immunovirotherapy; immunovirotherapy translational ... See more keywords
In Situ Cancer Vaccination and Immunovirotherapy Using Oncolytic HSV
Sign Up to like & getrecommendations! Published in 2021 at "Viruses"
DOI: 10.3390/v13091740
Abstract: Herpes simplex virus (HSV) can be genetically altered to acquire oncolytic properties so that oncolytic HSV (oHSV) preferentially replicates in and kills cancer cells, while sparing normal cells, and inducing anti-tumor immune responses. Over the… read more here.
Keywords: hsv; immunovirotherapy; oncolytic hsv; cancer ... See more keywords