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Published in 2021 at "Current Treatment Options in Rheumatology"
DOI: 10.1007/s40674-021-00174-1
Abstract: The idiopathic inflammatory myopathies are a heterogeneous group of autoimmune disorders characterized by skeletal muscle inflammation leading to chronic muscle weakness. Immune-mediated necrotizing myopathy (IMNM) is a distinct subgroup of inflammatory myopathy typically characterized by…
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Keywords:
autoantibody;
imnm;
treatment;
mediated necrotizing ... See more keywords
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Published in 2020 at "Nature Reviews Rheumatology"
DOI: 10.1038/s41584-020-00515-9
Abstract: Immune-mediated necrotizing myopathy (IMNM) is a group of inflammatory myopathies that was distinguished from polymyositis in 2004. Most IMNMs are associated with anti-signal recognition particle (anti-SRP) or anti-3-hydroxy-3-methylglutaryl-coA reductase (anti-HMGCR) myositis-specific autoantibodies, although ~20% of…
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Keywords:
muscle;
imnm;
mediated necrotizing;
immune mediated ... See more keywords
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Published in 2018 at "Current Opinion in Rheumatology"
DOI: 10.1097/bor.0000000000000547
Abstract: PURPOSE OF REVIEW In the past decade, immune-mediated necrotizing myopathies have emerged as a separate entity in the heterogenous group of autoimmune myopathies. This group is characterized by clinical manifestations restricted to the muscle tissue,…
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Keywords:
necrotizing myopathies;
muscle;
imnm;
mediated necrotizing ... See more keywords