Common framework mutations impact antibody interfacial dynamics and flexibility
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DOI: 10.3389/fimmu.2023.1120582
Abstract: Introduction With the flood of engineered antibodies, there is a heightened need to elucidate the structural features of antibodies that contribute to specificity, stability, and breadth. While antibody flexibility and interface angle have begun to… read more here.
Keywords: framework mutations; impact antibody; framework; common framework ... See more keywords