Impact of complement activation on clinical outcomes in multiple sclerosis
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DOI: 10.1002/acn3.51334
Abstract: We determined activation profiles of the classical and alternative complement pathway in 39 treatment‐naïve patients with early relapse‐onset MS. Plasma concentrations of complement fragments were unchanged in MS compared to 32 patients with non‐inflammatory neurological… read more here.
Keywords: impact complement; clinical outcomes; complement; activation ... See more keywords
Genetic Insights into the Impact of Complement in Alzheimer’s Disease
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DOI: 10.3390/genes12121990
Abstract: The presence of complement activation products at sites of pathology in post-mortem Alzheimer’s disease (AD) brains is well known. Recent evidence from genome-wide association studies (GWAS), combined with the demonstration that complement activation is pivotal… read more here.
Keywords: genetic insights; insights impact; disease; impact complement ... See more keywords