Articles with "impact cyp2c19" as a keyword



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Impact of CYP2C19 Phenotype and Drug-Drug Interactions on Voriconazole Concentration in Pediatric Patients

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Published in 2021 at "Antimicrobial Agents and Chemotherapy"

DOI: 10.1128/aac.00207-21

Abstract: Voriconazole (VRC), a first-line agent for the treatment of invasive fungal infections, is mainly metabolized by human cytochrome P450 (CYP) 2C19. In this study, a retrospective analysis was performed to investigate the key factors that… read more here.

Keywords: drug; pediatric patients; concentration; impact cyp2c19 ... See more keywords