The Necessary Nitrogen Atom: A Versatile High-Impact Design Element for Multiparameter Optimization.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.6b01807
Abstract: There is a continued desire in biomedical research to reduce the number and duration of design cycles required to optimize lead compounds into high-quality chemical probes or safe and efficacious drug candidates. The insightful application… read more here.
Keywords: necessary nitrogen; design; high impact; impact design ... See more keywords
Exploring the relationship between teachers’ flow-state and learning spaces: unraveling the impact of design conditions
Sign Up to like & getrecommendations! Published in 2024 at "Cogent Education"
DOI: 10.1080/2331186x.2024.2424155
Abstract: Abstract Flow-state is a condition where individuals are fully immersed in their mental abilities, wholeheartedly engaged in activities aimed at achieving peak performance. This study explores the relationships between teachers’ flow-state within three main learning… read more here.
Keywords: design conditions; flow state; teachers flow; impact design ... See more keywords
The Impact of Design Misspecifications on Survival Outcomes in Cancer Clinical Trials
Sign Up to like & getrecommendations! Published in 2025 at "Cancers"
DOI: 10.3390/cancers17162609
Abstract: Simple Summary Clinical trial design relies on assumptions that may change over time, potentially affecting the accuracy of results. This study evaluates how deviations in design assumptions impact the statistical power of randomized trials with… read more here.
Keywords: misspecifications survival; cancer clinical; impact design; outcomes cancer ... See more keywords